Patents Assigned to Evelo Biosciences, Inc.
  • Probiotic and prebiotic compositions, and methods of use thereof for modulation of the microbiome
    Patent number: 11672834
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: June 13, 2023
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Noubar B. Afeyan, Johanne Kaplan, Shaila Rahman
  • Probiotic compositions containing clostridiales for inhibiting inflammation
    Patent number: 11612622
    Abstract: Pharmaceutical compositions containing microbial entities are described herein. The pharmaceutical compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the pharmaceutical compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: March 28, 2023
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Johanne Kaplan, Shaila Rahman
  • Probiotic compositions containing clostridiales for inhibiting inflammation
    Patent number: 11607432
    Abstract: Pharmaceutical compositions containing microbial entities are described herein. The pharmaceutical compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the pharmaceutical compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: March 21, 2023
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Johanne Kaplan, Shaila Rahman
  • Bacterial extracellular vesicles
    Patent number: 11524037
    Abstract: Provided herein are methods and compositions related to EVs useful as therapeutic agents.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: December 13, 2022
    Assignee: Evelo Biosciences, Inc.
    Inventors: Brian Goodman, Baundauna Bose, Christopher J. H. Davitt
  • Compositions and methods for treating immune disorders using immune modulating bacteria strains
    Patent number: 11266700
    Abstract: Provided herein are methods and compositions related to immune modulating Lactococcus strains useful as therapeutic agents. In certain embodiments, provided herein are methods of treating an immune disorder in a subject comprising administering to the subject a bacterial composition comprising Lactococcus lactis cremoris Strain A (ATCC Deposit Number PTA-125368).
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: March 8, 2022
    Assignee: Evelo Biosciences, Inc.
    Inventors: Brian Goodman, Holly Ponichtera, Andrea Itano, Mark Bodmer, Taylor A. Cormack, Maria Sizova, Carolina Baez-Giangreco, Duncan McHale, Kritika Ramani
  • Treating cancer using a blautia strain
    Patent number: 11241461
    Abstract: Provided herein are methods and compositions related to Blautia Strain A useful as therapeutic agents.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: February 8, 2022
    Assignee: Evelo Biosciences, Inc.
    Inventors: Brian Goodman, Peter Sandy, Jacqueline Papkoff, Humphrey Gardner, Holly Ponichtera
  • Compositions and methods for treating cancer and immune disorders using bacteria
    Patent number: 11090341
    Abstract: Provided herein are methods and compositions related to Veillonella bacteria useful as therapeutic agents.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: August 17, 2021
    Assignee: Evelo Biosciences, Inc.
    Inventors: Brian Goodman, Baundauna Bose, Christopher J. H. Davitt, Maria Sizova, Sofia M. R. Carlton, Andrea Itano, Holly Ponichtera, Taylor A. Cormack, Kritika Ramani
  • Probiotic and prebiotic compositions, and methods of use thereof for modulation of the microbiome
    Patent number: 10980845
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: April 20, 2021
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Noubar B. Afeyan, Johanne Kaplan, Shaila Rahman
  • Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
    Patent number: 10869903
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial or fungal entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent transplant disorders, e.g., graft-versus-host disease (GVHD), in a subject are also provided.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: December 22, 2020
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Noubar B. Afeyan, Johanne Kaplan, Neal Gordon, Shaila Rahman
  • Compositions and methods of treating cancer using ssp.
    Patent number: 10792314
    Abstract: Provided herein are methods and compositions related to Bifidobacterium animalis ssp. lactis useful as therapeutic agents.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: October 6, 2020
    Assignee: Evelo Biosciences, Inc.
    Inventors: Peter Sandy, Jacqueline Papkoff, Maria Sizova, Brian Goodman, Humphrey Gardner, Holly Ponichtera, Hank Wu, William Caffry, Anupriya Dutta
  • Pharmaceutical compositions comprising a strain
    Patent number: 10702561
    Abstract: Provided herein are pharmaceutical compositions related to a Blautia strain useful as a therapeutic agent.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: July 7, 2020
    Assignee: Evelo Biosciences, Inc.
    Inventors: Brian Goodman, Holly Ponichtera, Andrea Itano, Taylor A. Cormack, Maria Sizova, Valeria Kravitz, Ekaterina Gavrish, Carolina Baez-giangreco
  • Method of treating cancer using ssp. strain PTA-125097
    Patent number: 10576111
    Abstract: Provided herein are methods and compositions related to Bifidobacterium animalis ssp. lactis useful as therapeutic agents.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: March 3, 2020
    Assignee: Evelo Biosciences, Inc.
    Inventors: Peter Sandy, Jacqueline Papkoff, Maria Sizova, Brian Goodman, Humphrey Gardner, Holly Ponichtera
  • Compositions and methods for treating disease using a strain
    Patent number: 10493113
    Abstract: Provided herein are methods and compositions related to Blautia Strain A useful as therapeutic agents.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: December 3, 2019
    Assignee: Evelo Biosciences, Inc.
    Inventors: Brian Goodman, Holly Ponichtera, Andrea Itano, Taylor A. Cormack, Maria Sizova, Valeria Kravitz, Ekaterina Gavrish, Carolina Baez-Giangreco
  • Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
    Patent number: 9603878
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial or fungal entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent transplant disorders, e.g., graft-versus-host disease (GVHD), in a subject are also provided.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: March 28, 2017
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Shaila Rahman, Johanne Kaplan, Neal Gordon