Abstract: A diagnostic tool 104 and method 300 are used to modify vascular age scoring systems using flow-mediated dilation (FMD) data. The resulting FMD-adjusted vascular age calculator can be used to diagnose a person's potential for developing cardiovascular disease.
Type:
Grant
Filed:
March 13, 2014
Date of Patent:
February 25, 2020
Assignee:
Everist Genomics, Inc.
Inventors:
Peter F. Lenehan, Thomas Stephen Everist, III
Abstract: A medical diagnostic system and method for assessing endothelial function comprise adjusting a reactive hyperemia indicator, measured in response to a stimulus, based on an anthropomorphic and/or demographic variable. The adjusted reactive hyperemia indicator provides a more accurate reflection of endothelial function and can be communicated to a clinician.
Type:
Grant
Filed:
July 1, 2016
Date of Patent:
November 26, 2019
Assignee:
Everist Genomics, Inc.
Inventors:
Peter F. Lenehan, Thomas Stephen Everist, III
Abstract: The invention relates to medicine. The inventive method for non-evasively determining an endothelial function consists in reducing a transmural pressure in a limb, recording the amplitude of plethysmographic signals at different pressures, determining the pressure of a maximum plethysmographic signal amplitude, reducing the pressure to a value corresponding to the specified percentage of the maximum amplitude, carrying out an occlusion sample in the course of which a pressure higher by at least 50 mm Hg than the systolic pressure of a tested patient is produced in a cuff arranged proximally to the located limb area, wherein the occlusion is carried out during at least 5 minutes.
Type:
Grant
Filed:
April 3, 2006
Date of Patent:
March 26, 2019
Assignee:
Everist Genomics, Inc.
Inventors:
Alexander Sergeevich Parfyonov, Maria Alexandrovna Parfyonova
Abstract: An assay system is useful for predicting recurrence and/or non-recurrence of colorectal cancer in a patient. The assay system is adapted to analyze a patient sample for quantitative expression of a prognostic genetic profile correlated with colorectal cancer recurrence. The profile includes the expression of the nucleic acid sequences of SEQ ID NOS: 1, 2, 3, 4, and 5.
Type:
Grant
Filed:
January 17, 2012
Date of Patent:
January 12, 2016
Assignee:
Everist Genomics, Inc.
Inventors:
William P. Worzel, Peter F. Lenehan, Arpit Almal, David W. Fry
Abstract: An assay system is useful for predicting recurrence and/or non-recurrence of colorectal cancer in a patient. The assay system is adapted to analyze a patient sample for quantitative expression of a prognostic genetic profile correlated with colorectal cancer recurrence. The profile includes the expression of the nucleic acid sequences of SEQ ID NOS: 1, 2, 3, 4, and 5.
Type:
Application
Filed:
January 17, 2012
Publication date:
July 19, 2012
Applicant:
Everist Genomics, Inc.
Inventors:
William P. Worzel, Peter F. Lenehan, Arpit Almal, David W. Fry