Abstract: An insertion assistance system includes a processor. The processor is configured to set a first position and a second position in shape information. The processor is configured to estimate a first state of a distal end of an insertion unit at the first position. The processor is configured to calculate a path through which the distal end passes. The processor is configured to determine a second state of the distal end at the second position. The processor is configured to output, to an information-reporting device, insertion assistance information required for an insertion operation for causing the distal end to reach the first position from the second position through the path and causing a state of the distal end to change from the second state to the first state.

Abstract: A microscope system includes an eyepiece-side observation optical system that forms an image of a sample on an object side of an eyepiece, a camera-side observation optical system that forms an image of the sample on an image sensor, a diaphragm that limits a numerical aperture on the emission side of the camera-side observation optical system, and a processor that analyzes the image of the sample captured by the image sensor. In a case where a numerical aperture on an object side of an objective lens is denoted by NA, the numerical aperture on the emission side of the camera-side observation optical system determined by a light flux emitted from the camera-side observation optical system toward the image sensor at capturing the image is denoted by NA?, and a total magnification of the camera-side observation optical system is denoted by M1, the following is satisfied.

Abstract: A two-dimensional image pickup device picks up an image of an image pickup target specimen on a stage. The focusing device changes a distance between the objective lens and the stage. A control unit acquires a specific parameter that is used for picking up an image of the image pickup target specimen and selected according to a type of the image pickup target specimen from among a plurality of parameters, each of which is used for picking up an image of each of a plurality of types of specimens. The control unit controls the stage, the two-dimensional image pickup device, and the focusing device on the basis of the specific parameter to acquire an image of the image pickup target specimen in each of a plurality of planes at different heights from the stage at each of a plurality of positions in a plane parallel to the stage.

Abstract: A measurement method includes a generation step, a region detection step, an image display step, a point input step, and a measurement step. Three-dimensional image data including three-dimensional coordinates of two or more points on a subject are generated in the generation step. Two or more feature regions on the subject are detected on the basis of the three-dimensional image data in the region detection step. An image of the two or more feature regions is displayed on a display in the image display step. A point on the subject is accepted through an input device in the point input step. A size of the subject is measured on the basis of three-dimensional coordinates of two or more points on the subject.

Abstract: A sample observation apparatus includes a light source unit, an illumination optical system, an observation optical system, a light detection element, a scanning unit, a holding member, and an image processing device. A light spot is formed by the illumination optical system. The scanning unit moves the light spot and the holding member relative to each other. A pupil of the observation optical system and the light detection element are positioned at a position conjugate to a pupil position of the illumination optical system. The image processing device generates an image of a sample based on a predetermined image and a filter, and the predetermined image is an image based on a signal output from the light detection element. The filter includes a first region and a second region, and a value in the first region is greater than a value in the second region.

Abstract: A score calculation device that calculates an image quality score of a microscopic image is provided with a processor. The processor acquires a generated image of a subject by inputting a microscopic image of the subject acquired using a microscope to an image generation model that outputs an output image with improved image quality from an input image, and calculates a score indicating similarity between the microscopic image and the generated image as an image quality score of the microscopic image.

Abstract: An imaging device sequentially acquires images of an observation target at a predetermined frame rate, and sequentially outputs trigger signals synchronized with frames. An illumination device can irradiate the observation target with illumination light from a plurality of illumination directions rotated about an optical axis of the objective lens around the optical axis, and switches the illumination directions according to the trigger signals. A computer generates a composite image representing a shape of the observation target on the basis of a plurality of images of the observation target acquired when the observation target is irradiated with the illumination light from the plurality of illumination directions.

Abstract: An objective includes: an objective barrel; a plurality of lens sub-assemblies stacked in an optical axis direction of the objective in the objective barrel, each of the plurality of lens sub-assemblies including a lens and a lens frame holding the lens; and a screw member screwed into the objective barrel, the screw member pressing the plurality of lens sub-assemblies against the objective barrel along the optical axis direction of the objective. The screw member has three or more concave portions into which a jig is fitted when the screw member is screwed into the objective barrel.

Abstract: A three-dimensional data generation method includes the following processing. A processor acquires two or more images of a component inside a turbine. The processor detects two or more correspondence regions that are the same regions in at least two images. The processor determines whether at least part of a region of each image is a change region or a non-change region. The processor generates three-dimensional data by using a correspondence region determined to be the change region without using a correspondence region determined to be the non-change region.

Abstract: A motorized correction collar system includes: an attachment portion; a control unit that controls transmission of force to a correction collar ring of a first objective lens attached to the attachment portion; and a storage unit that stores calibration information at least for each type of objective lens with a correction collar. The control unit acquires calibration information corresponding to the first objective lens from among the calibration information stored in the storage unit, and calibrates the correction collar of the first objective lens based on the calibration information.

Abstract: A microscope system comprises: a light source; an objective lens; a stage; a two-dimensional image sensor that captures an image of a specimen placed on the stage; a focusing device that changes distance between the objective lens and the stage; and a control circuit, wherein the control circuit executes, during a movement period in which the stage moves in a direction orthogonal to an optical axis of the objective lens, focus control for controlling the focusing device based on focus evaluation information detected during the movement period, and exposure control for controlling an exposure period of the two-dimensional image sensor, and executes light emission control that causes the light source to emit light with different light emission intensities during the exposure period and during a focus evaluation period in which the focus evaluation information is detected.

Abstract: An image capturing device for observing a sample housed in a container includes: an image capturing unit; a light guide unit that guides light from an identification surface to the image capturing unit, the identification surface being a surface of the container different from a bottom surface of the container and to which identification information is attached; and a mobile unit that changes a relative position of the image capturing unit with respect to the container. In a first relative position in which the optical axis of the image capturing unit deviates from the container, the image capturing unit images the identification surface via the light guide unit. In a second relative position in which the optical axis of the image capturing unit intersects the container, the image capturing unit images the sample via the bottom surface.

Abstract: The objective includes a first lens group having positive power and a second lens group having negative power and including a pair of meniscus lens components having concave surfaces facing each other. The first lens group includes a first lens situated closest to an object side and has positive power with a concave surface facing the object side. The objective includes three or more cemented lenses arranged closer to the object side than the pair of meniscus lens components, and satisfies the following conditional expressions. 2.6 ? ? L ? 1 / D L ? 1 ? 16 ( 1 ) 0.1 ? ? "\[LeftBracketingBar]" R 2 ? 1 ? 2 ? "\[RightBracketingBar]" / f ? 3.5 ( 2 ) Here, ?L1 and DL1 are an outer diameter and a thickness of the first lens. R212 is a radius of curvature of a surface closest to the image side in a first meniscus lens component among the pair of meniscus lens components. f is a focal length of the objective.

Abstract: A microscope system includes: a motorized nosepiece configured to hold a plurality of objective lenses and be able to switch the objective lenses arranged on an observation optical path by rotation; and a processor configured to control driving of the motorized nosepiece in accordance with an input drive instruction, in which the processor has, as a switchable mode for controlling driving of the motorized nosepiece, a first mode for switching the objective lenses arranged on the observation optical path by rotating the motorized nosepiece with a first rotation amount corresponding to the drive instruction, in accordance with the drive instruction, and a second mode for rotating the motorized nosepiece with a second rotation amount in accordance with the drive instruction, and the second rotation amount is smaller than the first rotation amount.

Abstract: An objective includes, in order from an object side: a first lens group having positive refractive power and including three or more lens components; a second lens group having a highest light ray height and moving on an optical axis; a third lens group including a lens component having a concave surface facing an image side and closest to the image side of the third lens group; and a fourth lens group including a lens component having a concave surface facing an object side and closest to the object side of the fourth lens group, in which the first lens group includes a cemented lens closer to the image side than the lens component closest to the object side of the first lens group.

Abstract: A frame image extraction method including: during recording processing of a moving image including a plurality of frame images generated on a basis of an imaging signal output from an imaging element included in an insertion portion inserted into a test subject, among the plurality of frame images, adding, as a tag, information regarding an operation to a frame image corresponding to a timing when an operation receiving unit receives the operation, and adding, as a tag, information regarding a specific feature image to a frame image recognized as the specific feature image; and extracting a frame image from among the plurality of frame images included in the moving image on a basis of at least one type of tag among two or more types of tags selected from among a plurality of types of the tags.

Abstract: A non-transitory computer-readable medium storing a program for causing a processor to at least execute processing of: during recording processing of a moving image including a plurality of frame images generated on a basis of an imaging signal output from an imaging element included in an insertion portion inserted into a test subject, among the plurality of frame images, adding, as a tag, information regarding an operation to a frame image corresponding to a timing when an operation receiving unit receives the operation, and adding, as a tag, information regarding a specific feature image to a frame image recognized as the specific feature image; and extracting a frame image from among the plurality of frame images included in the moving image on a basis of at least one type of tag among two or more types of tags selected from among a plurality of types of the tags.

Abstract: A motorized correction collar system includes: an attachment portion; a control unit that controls transmission of force to a correction collar ring of a first objective lens attached to the attachment portion; and a storage unit that stores calibration information at least for each type of objective lens with a correction collar. The control unit acquires calibration information corresponding to the first objective lens from among the calibration information stored in the storage unit, and calibrates the correction collar of the first objective lens based on the calibration information.

Abstract: A microscope apparatus includes a color temperature adjustment unit. The color temperature adjustment unit includes, in order from an incident side of light: a first polarizer that converts the light into linearly polarized light; a ¼-wave plate that converts at least light of a predetermined wavelength of the linearly polarized light into circularly polarized light, the ¼-wave plate being fixed in a predetermined orientation relative to the first polarizer; and a second polarizer that extracts a predetermined polarization component, the second polarizer being disposed to be rotatable relative to the first polarizer. A difference between a phase amount with respect to light of 435 nm and a phase amount with respect to light of 635 nm of the ¼-wave plate is 30 degrees or more.

Abstract: A microscope used in multiple microscopies includes an objective used in common in the multiple microscopies, and a magnification adjustment device arranged on an image side of the objective and configured to adjust an optical magnification of the microscope in response to switching of the multiple microscopies.