Abstract: Topical skin treatment formulation containing salicylic acid or a derivative thereof, dissolved in a solvent system comprising (i) dimethyl isosorbide; (ii) a C1 to C9 alkyl salicylate; and (iii) a glyceryl fatty acid ester. The solvent system may also comprise an alcohol, a polyoxyalkylene-based solvent, and/or a C1 to C4 alkyl glucose ester. The formulation may be used in the treatment of acne. The solvent system improves the targeted delivery of the salicylic acid or derivative to relevant sites on the skin.
Type:
Application
Filed:
March 26, 2012
Publication date:
April 17, 2014
Applicant:
EVOCUTIS PLC
Inventors:
Steven John Abbott, Jonathan Howard Cove, Gavin Donoghue, Sarah-Jayne Gregory
Abstract: Topical skin treatment formulation containing usnic acid or an usnate salt, dissolved in a solvent system comprising (i) dimethyl isosorbide; (ii) a C1 to C9 alkyl salicylate; and (iii) a glyceryl fatty acid ester. The solvent system may also comprise an alcohol, a polyoxyalkylene-based solvent, and/or a C1 to C4 alkyl glucose ester. The formulation may be used in the treatment of microbial conditions, in particular acne. The solvent system assists in the effective dissolution of the usnic acid or usnate and in targeting its delivery to relevant sites on the skin.
Type:
Application
Filed:
March 26, 2012
Publication date:
February 27, 2014
Applicant:
EVOCUTIS PLC
Inventors:
Steven John Abbott, Gavin Donoghue, Elizabeth Anne Eady
Abstract: An antibacterial or anti-acne formulation suitable for topical or local application to human skin containing (a) either usnic acid or an usnate and (b) a metal salt selected from copper salts, bismuth salts, and mixtures thereof, wherein if the component (a) is an usnate, the components (a) and (b) are not the same compound.
Type:
Application
Filed:
December 20, 2011
Publication date:
November 28, 2013
Applicant:
EVOCUTIS PLC
Inventors:
Elizabeth Anne Eady, Daniel James Fitzgerald
Abstract: An antibacterial or anti-acne formulation containing (a) tropone or a substituted tropone and (b) a metal or metal salt selected from copper, copper salts, bismuth, bismuth salts, silver, silver salts, and mixtures thereof, for use in the treatment of either acne or body odour. The substituted tropone may be for example tropolone or hinokitiol.
Type:
Application
Filed:
July 25, 2011
Publication date:
August 15, 2013
Applicant:
EVOCUTIS PLC
Inventors:
Jonathan Cove, Daniel Fitzgerald, Nicholas Read
Abstract: An antimicrobial and/or anti-acne formulation containing either usnic acid or an usnate, together with (a) a primary solvent or solvent system in which the usnic acid or usnate is at least partially dissolved; (b) a glycol; and (c) a hydrophobic fatty acid, fatty alcohol or derivative thereof. The formulation may also contain (d) an alkylene glycol derivative.
Type:
Application
Filed:
November 1, 2010
Publication date:
October 25, 2012
Applicant:
EVOCUTIS PLC
Inventors:
Adrian Davis, Gavin Donoghue, Elizabeth Eady