Patents Assigned to Evolutionary Genomics, Inc.
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Patent number: 9605274Abstract: The present invention provides the identification and use of EG261, homologs of EG261, orthologs of EG261, paralogs of EG261, and fragments and variations thereof for altering, e.g. increasing, pathogen tolerance and/or resistance in plants.Type: GrantFiled: September 8, 2014Date of Patent: March 28, 2017Assignee: Evolutionary Genomics, Inc.Inventor: Walter Messier
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Publication number: 20160032306Abstract: The present invention provides the identification and use of EGTom1 and/or EGTom2, homologs of EGTom1 and/or EGTom2, orthologs of EGTom1 and/or EGTom2, paralogs of EGTom1 and/or EGTom2, and fragments and variations thereof for altering salt tolerance, drought tolerance and/or sugar content of fruit (sweetness) in plants. The invention relates to the identification and use of nucleic acid sequences for salt/drought tolerance and fruit sweetness in plants.Type: ApplicationFiled: March 14, 2014Publication date: February 4, 2016Applicant: Evolutionary Genomics, inc.Inventor: Walter Messier
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Publication number: 20140380518Abstract: The present invention provides the identification and use of EG261, homologs of EG261, orthologs of EG261, paralogs of EG261, and fragments and variations thereof for altering, e.g. increasing, pathogen tolerance and/or resistance in plants.Type: ApplicationFiled: September 8, 2014Publication date: December 25, 2014Applicant: Evolutionary Genomics, Inc.Inventor: Walter Messier
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Patent number: 8710300Abstract: The present invention provides for the identification and use of EG261, homologs of EG261, orthologs of EG261, and paralogs of EG261. Modulation of the expression of EG261 in plants can alter pathogen tolerance and/or resistance e.g. expression of EG261 can confer soybeans with enhanced tolerance and/or resistance to soybean cyst nematodes.Type: GrantFiled: July 23, 2013Date of Patent: April 29, 2014Assignee: Evolutionary Genomics IncInventor: Walter Messier
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Publication number: 20140068807Abstract: The present invention provides the identification and use of EG261, homologs of EG261, orthologs of EG261, paralogs of EG261, and fragments and variations thereof for altering, e.g. increasing, pathogen tolerance and/or resistance in plants.Type: ApplicationFiled: May 23, 2013Publication date: March 6, 2014Applicant: Evolutionary Genomics, Inc.Inventor: Walter MESSIER
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Publication number: 20120073020Abstract: The present invention provides methods for identifying polynucleotide and polypeptide sequences which may be associated with commercially or aesthetically relevant traits in domesticated plants or animals. The methods employ comparison of homologous genes from the domesticated organism and its ancestor to identify evolutionarily significant changes and evolutionarily neutral changes. Sequences thus identified may be useful in enhancing commercially or aesthetically desirable traits in domesticated organisms or their wild ancestors.Type: ApplicationFiled: November 28, 2011Publication date: March 22, 2012Applicant: EVOLUTIONARY GENOMICS, INC.Inventor: Walter Messier
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Publication number: 20110173723Abstract: The present invention provides methods for identifying nucleic acid and polypeptide sequences which may be associated with a commercially relevant trait in plants, specifically, so-identified nucleic acids and polypeptide sequences for yield genes EG82013 and EG81345. Sequences thus identified are useful in enhancing commercially desired traits in domesticated plants or wild ancestor plants, identifying related nucleic acid sequences, genotyping a plant, and marker assisted breeding. Sequences thus identified may also be used to generate heterologous DNA, transgenic plants, and transfected host cells.Type: ApplicationFiled: July 29, 2009Publication date: July 14, 2011Applicant: EVOLUTIONARY GENOMICS, INC.Inventor: Walter Messier
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Publication number: 20110083229Abstract: The present invention provides methods for identifying polynucleotide and polypeptide sequences which may be associated with a commercially relevant trait in plants, specifically, so-identified polynucleotides and polypeptide sequences for yield-related genes EG307 and EG1117 for corn, wheat, barley, sorghum, and sugarcane. Sequences thus identified are useful in enhancing commercially desired traits in domesticated plants or wild ancestor plants, identifying related polynucleotide sequences, genotyping a plant, and marker assisted breeding. Sequences thus identified may also be used to generate heterologous DNA, transgenic plants, and transfected host cells.Type: ApplicationFiled: December 10, 2010Publication date: April 7, 2011Applicant: EVOLUTIONARY GENOMICS, INC.Inventor: Walter Messier
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Publication number: 20100159440Abstract: The present invention provides methods for identifying evolutionarily significant polynucleotide and polypeptide sequences in human and/or non-human primates which may be associated with a physiological condition, such as enhanced resistance to HCV infection. The invention also provides methods for identifying evolutionarily significant polynucleotides with mutations that are correlated with susceptibility to diseases, such as BRCA1 exon 11. The methods employ comparison of human and non-human primate sequences using statistical methods. Sequences thus identified may be useful as host therapeutic targets and/or in screening assays.Type: ApplicationFiled: December 9, 2008Publication date: June 24, 2010Applicant: Evolutionary Genomics, Inc.Inventors: Walter Messier, James Sikela
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Publication number: 20090304653Abstract: Disclosed are methods to identify an agent which may modulate resistance to HIV-1-mediated disease, comprising contacting at least one agent to be tested with a cell comprising human ICAM-1, and detecting the cell's resistance to HIV-1 viral replication, propagation, or function, wherein an agent is identified by its ability to increase the cell's resistance to HIV-1 viral replication, propagation, or function. Also disclosed are human mutant ICAM-1 polypeptides and methods to treat HIV-1 viral replication, propagation, or function in a human subject by ICAM-1 gene therapy relating to one or more of the following 10 mutations to human ICAM-1: L18Q, K29D, P45G, R49W, E171Q, wherein the mutant ICAM-1 is otherwise identical to human ICAM-1.Type: ApplicationFiled: April 6, 2009Publication date: December 10, 2009Applicant: EVOLUTIONARY GENOMICS, INC.Inventor: Walter Messier
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Publication number: 20090133164Abstract: The present invention provides methods for identifying polynucleotide and polypeptide sequences which may be associated with commercially or aesthetically relevant traits in domesticated plants or animals. The methods employ comparison of homologous genes from the domesticated organism and its ancestor to identify evolutionarily significant changes and evolutionarily neutral changes. Sequences thus identified may be useful in enhancing commercially or aesthetically desirable traits in domesticated organisms or their wild ancestors.Type: ApplicationFiled: October 21, 2008Publication date: May 21, 2009Applicant: EVOLUTIONARY GENOMICS, INC.Inventor: Walter Messier
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Patent number: 7462460Abstract: The present invention provides methods for identifying evolutionarily significant polynucleotide and polypeptide sequences in human and/or non-human primates which may be associated with a physiological condition, such as enhanced resistance to HCV infection. The invention also provides methods for identifying evolutionarily significant polynucleotides with mutations that are correlated with susceptibility to diseases, such as BRCA1 exon 11. The methods employ comparison of human and non-human primate sequences using statistical methods. Sequences thus identified may be useful as host therapeutic targets and/or in screening assays.Type: GrantFiled: February 15, 2005Date of Patent: December 9, 2008Assignee: Evolutionary Genomics, Inc.Inventors: Walter Messier, James Sikela
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Patent number: 7439018Abstract: The present invention provides methods for identifying polynucleotide and polypeptide sequences which may be associated with commercially or aesthetically relevant traits in domesticated plants or animals. The methods employ comparison of homologous genes from the domesticated organism and its ancestor to identify evolutionarily significant changes and evolutionarily neutral changes. Sequences thus identified may be useful in enhancing commercially or aesthetically desirable traits in domesticated organisms or their wild ancestors.Type: GrantFiled: January 16, 2003Date of Patent: October 21, 2008Assignee: Evolutionary Genomics, Inc.Inventor: Walter Messier
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Publication number: 20080256659Abstract: The present invention provides methods for identifying polynucleotide and polypeptide sequences which may be associated with a commercially relevant trait in plants, specifically, so-identified polynucleotides and polypeptide sequences for yield-related genes EG9703 and EG8798 for rice, corn, wheat, barley, sorghum, and sugarcane. Sequences thus identified are useful in enhancing commercially desired traits in domesticated plants or wild ancestor plants, identifying related polynucleotide sequences, genotyping a plant, and marker assisted breeding. Sequences thus identified may also be used to generate heterologous DNA, transgenic plants, and transfected host cells.Type: ApplicationFiled: September 5, 2006Publication date: October 16, 2008Applicant: EVOLUTIONARY GENOMICS, INC.Inventor: Walter Messier