Abstract: The inventions described herein relate generally to the use of compositions to increase output of acetate and lactate while reducing pH and the levels of pathogenic bacteria and inflammation in the gut of a nursing infant mammal including humans. These compositions generally comprise one or more bacterial strains selected for their growth on mammalian milk oligosaccharides, a source of mammalian milk oligosaccharides, and, optionally, nutritive components required for the growth of that infant mammal.
Type:
Grant
Filed:
June 30, 2017
Date of Patent:
May 3, 2022
Assignee:
EVOLVE BIOSYSTEMS, INC.
Inventors:
David Kyle, Steven Frese, Samara Freeman-Sharkey, Bethany Henrick
Abstract: Some embodiments of the invention include a composition and method for treating dysbiosis in infants. The composition may include a mixture of activated bifidobacteria and a complex oligosaccharide wherein the complex oligosaccharide may be derived from a human or non-human source.
Type:
Grant
Filed:
October 23, 2015
Date of Patent:
July 21, 2020
Assignee:
EVOLVE BIOSYSTEMS INC.
Inventors:
David Kyle, David Mills, Samara Freeman-Sharkey
Abstract: Some embodiments of the invention include a composition and method for treating dysbiosis in infants. The composition may include a mixture of activated bifidobacteria and a complex oligosaccharide wherein the complex oligosaccharide may be derived from a human or non-human source.
Type:
Application
Filed:
October 23, 2015
Publication date:
October 26, 2017
Applicant:
EVOLVE BIOSYSTEMS INC
Inventors:
David KYLE, David MILLS, Samara FREEMAN-SHARKY