Abstract: Disclosed are peptides which specifically bind to preselected pre-miRNA or pri-miRNA targets, methods of down-regulating EMT in a cell using such peptides, and methods of preparing such peptides. Also provided are therapeutic compositions comprising peptides that specifically bind a preselected cancer marker which is a peptide or which is a pre-miRNA or a pri-miRNA and methods of treatment using the same.
Type:
Grant
Filed:
May 14, 2015
Date of Patent:
June 18, 2019
Assignee:
EVORX TECHNOLOGIES, INC.
Inventors:
Stephen V. Fiacco, Amanda N. Hardy, Terry T. Takahashi
Abstract: Disclosed are highly potent peptides, peptide conjugates, host cells and compositions containing one or more of these peptides, peptide conjugates and/or host cells that are useful to inhibit the growth of a breast cancer cell or treat breast cancer in a patient in need of such treatment.