Abstract: A process for instabilizing viral quasi-species-distributions under avoidance of resistance phenomena by replication of the nucleic acids of the viruses present in the quasi-species-distribution by of a defective replication system,
Type:
Application
Filed:
October 25, 2001
Publication date:
August 8, 2002
Applicant:
EVOTECH BIOSYSTEMS AG
Inventors:
Manfred Eigen, Andreas Schwienhorst, Christof Biebricher, Bjorn Lindemann, Esteban Domingo, John Holland, Karsten Henco