Abstract: Novel thiazole- and/or isoquinoline-containing compounds are presented that are useful for treating cancers as well as treating and/or preventing viral infections. Methods of treating and/or preventing broad-spectrum viral infections are also presented. These compounds have been shown to inhibit HCMV, influenza virus, and coronavirus replication in cell-based assays.
Type:
Application
Filed:
December 30, 2021
Publication date:
April 4, 2024
Applicant:
Evrys Bio, LLC
Inventors:
STACY REMISZEWSKI, LILLIAN W. CHIANG, FRANK KAYSER, SARAH JOCELYN FINK
Abstract: Novel thiazole- and isoquinoline-containing compounds are presented that are useful for treating and/or preventing broad-spectrum viral infections. Methods of treating and/or preventing broad-spectrum viral infections are also presented. These compounds have shown inhibition of HCMV, influenza viruses, Zika virus, BK Virus and RSV replication in cell-based assays.
Type:
Application
Filed:
July 14, 2022
Publication date:
December 28, 2023
Applicant:
Evrys Bio, LLC
Inventors:
Stacy Remiszewski, Lillian W. Chiang, Eain Anthony Murphy, Qun Sun, Frank Kayser, Sarah Jocelyn Fink
Abstract: Novel thiazole- and isoquinoline-containing compounds are presented that are useful for treating and/or preventing broad-spectrum viral infections. Methods of treating and/or preventing broad-spectrum viral infections are also presented. These compounds have shown inhibition of HCMV, influenza viruses, Zika virus, BK Virus and RSV replication in cell-based assays.
Type:
Grant
Filed:
October 17, 2018
Date of Patent:
October 4, 2022
Assignee:
Evrys Bio, LLC
Inventors:
Stacy Remiszewski, Lillian W. Chiang, Eain Anthony Murphy, Qun Sun, Frank Kayser, Sarah Jocelyn Fink
Abstract: Novel thiazole- and isoquinoline-containing compounds are presented that are useful for treating and/or preventing broad-spectrum viral infections. Methods of treating and/or preventing broad-specturm viral infections are also presented. These compounds have shown inhibition of HCMV, influenza viruses, Zika virus, BK Virus and RSV replication in cell-based assays.
Type:
Application
Filed:
October 17, 2018
Publication date:
May 13, 2021
Applicant:
Evrys Bio, LLC
Inventors:
Stacy Remiszewski, Lillian W. Chiang, Eain Anthony Murphy, Qun Sun, Frank Kayser, Sarah Jocelyn Fink