Abstract: This invention provides a system and method for providing Indicator Features in high resolution micro-ultrasound prostate images, wherein the ultrasound device operates at a center frequency of 15 MHz and above. Indicator Features are features, which have been identified alone and/or in combination with other features in high resolution micro-ultrasound images, and have been determined to be significantly statistically correlated to either benign tissue or some grade of cancerous tissue on the basis of predictive probabilities. These Indicator Features can be used to train a linear or non-linear classifier, which can be used to classify patient images of the prostate. These Indicator Features can be used to guide a clinician as to where to take a biopsy core from the prostate, as well as assist in diagnosis of the tissue.

Abstract: The present invention provides improved medical imaging apparatuses, systems and methods, especially those using ultrasonography. For example, an imaging system can include a transducer, a scanner, a signal processing unit, and a display unit. The scanner, coupled to the transducer, can convert analog signals to a plurality of digital signals. The signal processing unit, coupled to the scanner, can be configured to: receive the plurality of digital signals; multiply a first magnitude estimate of the plurality of digital signals by a probability that an actual magnitude of the plurality of digital signals is greater than zero to determine a second magnitude; and form an image based on the second magnitude estimate. The display unit displays the image. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention.