Patents Assigned to Exagen Diagnostics, Inc.
  • Methods for diagnosing systemic lupus erythematosus
    Patent number: 10132813
    Abstract: The present invention provides methods of diagnosing and monitoring systemic lupus erythematosus.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: November 20, 2018
    Assignee: Exagen Diagnostics, Inc.
    Inventors: Thierry Dervieux, Cole Harris
  • Methods for treating and diagnosing Systemic Lupus Erythematosus
    Publication number: 20150369824
    Abstract: Methods and reagents for diagnosing, prognosing, and treating systemic lupus erythematosus (SLE) are disclosed, involving calculating an SLE risk score for a subject based on a level of each of an erythrocyte C4d (EC4d) marker, a B-cell C4d (BC4d) marker, antinuclear antibodies (ANA), anti-Smith antibodies (anti-Sm) and optional rule-out markers (SS-B/La, Scl-70, Jo-1, CENP, MCV).
    Type: Application
    Filed: March 13, 2014
    Publication date: December 24, 2015
    Applicant: EXAGEN DIAGNOSTICS, INC.
    Inventors: Thierry DERVIEUX, Derren BARKEN
  • Methods for Diagnosing Systemic Lupus Erythematosus
    Publication number: 20130309698
    Abstract: The present invention provides methods of diagnosing and monitoring systemic lupus erythematosus.
    Type: Application
    Filed: February 10, 2012
    Publication date: November 21, 2013
    Applicant: EXAGEN DIAGNOSTICS, INC.
    Inventors: Thierry Dervieux, Cole Harris
  • Methods for optimizing biological response modifier therapy using therapeutic drug monitoring of immunosuppressants
    Publication number: 20130216530
    Abstract: The invention provides methods for treating humans in need of combined immunosuppressant and biological response modifier therapy.
    Type: Application
    Filed: February 1, 2013
    Publication date: August 22, 2013
    Applicant: Exagen Diagnostics, Inc.
    Inventor: Exagen Diagnostics, Inc.
  • Biomarkers for Ulcerative Colitis and Crohn's Disease
    Publication number: 20130079245
    Abstract: The present invention provides compositions and their use in diagnosing ulcerative colitis, Crohn's Disease, and inflammatory bowel disease.
    Type: Application
    Filed: November 28, 2012
    Publication date: March 28, 2013
    Applicant: EXAGEN DIAGNOSTICS, INC.
    Inventor: Exagen Diagnostics, Inc.
  • BIOMARKERS FOR SYSTEMIC LUPUS ERYTHEMATOSUS
    Publication number: 20130065229
    Abstract: The present invention provides methods and reagents for diagnosing system lupus erythematosus and for monitoring system lupus erythematosus disease activity in a subject.
    Type: Application
    Filed: June 25, 2012
    Publication date: March 14, 2013
    Applicant: EXAGEN DIAGNOSTICS, INC.
    Inventors: Cole Harris, Tracy Costello
  • Genes predictive of anti-TNF response in inflammatory diseases
    Publication number: 20130040835
    Abstract: The present invention provides compositions and their use in predicting anti-tumor necrosis factor therapy response in a patient with an inflammatory disease.
    Type: Application
    Filed: May 4, 2012
    Publication date: February 14, 2013
    Applicant: EXAGEN DIAGNOSTICS, INC
    Inventor: Cole Harris
  • Biomarkers for inflammatory bowel disease and irritable bowel syndrome
    Patent number: 8227589
    Abstract: The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: July 24, 2012
    Assignee: Exagen Diagnostics, Inc.
    Inventors: Cole Harris, John Alsobrook
  • Biomarkers for inflammatory bowel disease and irritable bowel syndrome
    Patent number: 8222390
    Abstract: The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: July 17, 2012
    Assignee: Exagen Diagnostics, Inc.
    Inventors: Cole Harris, John Alsobrook
  • Biomarkers for Ulcerative Colitis and Crohn's Disease
    Publication number: 20110301051
    Abstract: The present invention provides compositions and their use in diagnosing ulcerative colitis, Crohn's Disease, and inflammatory bowel disease.
    Type: Application
    Filed: April 8, 2011
    Publication date: December 8, 2011
    Applicant: Exagen Diagnostics, Inc.
    Inventors: Cole Harris, John Alsobrook, Lisa Davis
  • Pharacogenetic method for prediction of the efficacy of methotrexate monotherapy in recent-onset arthritis
    Patent number: 8073630
    Abstract: Pharmacogenetic methods for determining a predicting responsiveness to antifolate therapy for subjects that present with recent-onset undifferentiated arthritis. The methods are based on the determination of a set of clinical parameter values and determining a predicted responsiveness to antifolate therapy by correlating the parameter values with predefined responsiveness values associated with ranges of parameter values. Parameters values that are decisive for responsiveness to antifolate therapy may include polymorphisms in the methylenetetrahydrofolate dehydrogenase (MTHFD1) gene as well as in three genes involved in the adenosine release pathway, the presence or absence of Rheumatoid factors, gender, pre- or postmenopausal status and/or smoking status.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: December 6, 2011
    Assignee: Exagen Diagnostics, Inc.
    Inventors: Hendrik Jan Guchelaar, Tom Willem Johannes Huizinga
  • Methods of Quantifying Methotrexate Metabolites
    Publication number: 20110262948
    Abstract: The present invention provides a method for efficiently converting methotrexate polyglutamates to methotrexate in a cellular extract by contacting the cellular extract with gamma glutamyl hydrolase under conditions suitable for efficient conversion of methotrexate polyglutamates to methotrexate.
    Type: Application
    Filed: June 10, 2011
    Publication date: October 27, 2011
    Applicant: Exagen Diagnostics, Inc.
    Inventors: Thierry Dervieux, Russell B. Richerson
  • Cell-Based Complement Activation Product Algorithm for Diagnosing Systemic Lupus Erythematosus
    Publication number: 20110177531
    Abstract: The present invention provides methods of diagnosing and monitoring systemic lupus erythematosus by measuring cell-based complement activation products (CB-CAPS) in a subject's blood. In particular, the invention describes a diagnostic method employing the measurement of multiple complement activation products on the surfaces of red blood cells, white blood cells, and platelets (e.g., EC4d, BC4d, PC4d, and ECR1). A diagnostic algorithm utilizing the determined levels of CB-CAPS is also disclosed.
    Type: Application
    Filed: October 15, 2010
    Publication date: July 21, 2011
    Applicant: EXAGEN DIAGNOSTICS, INC.
    Inventors: Thierry DERVIEUX, Michael GENDREAU, Rong ZABLOCKI
  • Biomarkers for inflammatory bowel disease and irritable bowel syndrome
    Patent number: 7923544
    Abstract: The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: April 12, 2011
    Assignee: Exagen Diagnostics, Inc.
    Inventors: Cole Harris, John Alsobrook
  • Biomarkers for inflammatory bowel disease and irritable bowel syndrome
    Patent number: 7879553
    Abstract: The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: February 1, 2011
    Assignee: Exagen Diagnostics, Inc.
    Inventors: Cole Harris, John Alsobrook
  • Biomarkers for inflammatory bowel disease and irritable bowel syndrome
    Patent number: 7833720
    Abstract: The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: November 16, 2010
    Assignee: Exagen Diagnostics, Inc.
    Inventors: Cole Harris, John Alsobrook
  • Biomarkers for inflammatory bowel disease and irritable bowel syndrome
    Patent number: 7833721
    Abstract: The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: November 16, 2010
    Assignee: Exagen Diagnostics, Inc.
    Inventors: Cole Harris, John Alsobrook
  • Biomarkers for Inflammatory Bowel Disease and Irritable Bowel Syndrome
    Publication number: 20100184967
    Abstract: The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome.
    Type: Application
    Filed: March 29, 2010
    Publication date: July 22, 2010
    Applicant: EXAGEN DIAGNOSTICS, INC.
    Inventors: Cole Harris, John Alsobrook
  • Biomarkers for Inflammatory Bowel Disease and Irritable Bowel Syndrome
    Publication number: 20100184625
    Abstract: The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome.
    Type: Application
    Filed: March 29, 2010
    Publication date: July 22, 2010
    Applicant: EXAGEN DIAGNOSTICS, INC.
    Inventors: Cole Harris, John Alsobrook
  • Compositions and Methods for Breast Cancer Prognosis
    Publication number: 20100159469
    Abstract: The present invention provides novel compositions and their use in classifying breast tumors.
    Type: Application
    Filed: February 24, 2010
    Publication date: June 24, 2010
    Applicant: EXAGEN DIAGNOSTICS, INC.
    Inventors: Cole Harris, Lisa Davis