Abstract: The present invention relates to fluorescent dyes of formula (I), including salts thereof, and extracellular vesicles and cells labelled with the fluorescent dyes. The present invention also relates to methods, uses and kits thereof.
Type:
Application
Filed:
December 24, 2021
Publication date:
March 21, 2024
Applicant:
EXOPHARM LIMITED
Inventors:
Jim PALMER, Ian DIXON, Patrick JAMES, Melanie SCHOPPET, Karmen KONG, Sebastian M. MARCUCCIO, Jonathan M. FABER, Kieran P. STOCKTON, Melissa WERRETT, Rohan JOYCE
Abstract: The invention provides methods and compositions for the isolation or extraction of exosomes or microvesicles. The methods and compositions may involve providing a device including exosome-binding ligands in the form of anionic or electron-rich groups arranged on a substrate surface. The methods and compositions may involve providing a device including a substrate having a surface, with a plurality of polymers attached to the substrate and exosome-binding ligands in the form of anionic or electron-rich groups arranged on the plurality of polymers.
Type:
Application
Filed:
June 18, 2019
Publication date:
August 12, 2021
Applicant:
Exopharm Limited
Inventors:
Gregor Lichtfuss, Jim Palmer, Ian Dixon