Patents Assigned to EXORNA BIOSCIENCE (NANJING) CO. LTD.
  • SIRNA FOR INHIBITING HTT GENE EXPRESSION, AND PRECURSOR AND APPLICATION THEREOF
    Publication number: 20220356473
    Abstract: The present invention provides a siRNA for inhibiting HTT gene expression and a precursor thereof, an expression vector comprising the siRNA or the precursor thereof, application thereof in preparation of a drug for treating Huntington's disease, and a pharmaceutical formulation and pharmaceutical composition containing the siRNA, the precursor or the expression vector. The siRNA is selected from the following: SEQ ID NO:1, SEQ ID NO:2. SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, or a combination thereof.
    Type: Application
    Filed: November 27, 2020
    Publication date: November 10, 2022
    Applicants: EXORNA BIOSCIENCE (NANJING) CO. LTD., EXORNA BIOSCIENCE (SHANGHAI) CO. LTD.
    Inventors: Xi CHEN, Li ZHANG, Zhong PEI, Tengteng WU, Jin LIU, Mengchao YU, Yugui XIA, Sheng TU, Qiaofang LIN