Patents Assigned to Exosomics Siena S.p.A.
  • Method and a kit to quantify and qualify exosomes for diagnosis of prostate cancer and prostate hyperplasia
    Publication number: 20170307635
    Abstract: A method and a kit are provided to quantify and qualify exosomes. Specifically the method and the kit quantify PSA-carrying exosomes for a purpose to diagnose prostate cancer and to distinguish between patients having a tumor and those having a benign prostate condition with increased blood levels of PSA. The method and the kit provide a fast, easy to use and accurate method for clinical settings.
    Type: Application
    Filed: July 8, 2017
    Publication date: October 26, 2017
    Applicant: Exosomics Siena S.p.A.
    Inventors: Stefano Fais, Mariantonia Logozzi, Ruggero De Maria Marchiano, Desiree Bonci
  • Use of TM9SF4 as a biomarker for tumor associated exosomes
    Publication number: 20170146543
    Abstract: The present invention relates to extracellular microvesicles biomarkers for determining the tumour transformation status or presence of a tumour in a subject, and to the uses of such biomarkers and to diagnostics methods using such biomarkers. In particular, the methods and uses of the invention involve isolation of TM9SF4-positive extracellular vesicles and detection of the expression of a second biomarker, preferably selected from the group consisting of CD9 protein, miR-21 and RNU6.
    Type: Application
    Filed: June 5, 2015
    Publication date: May 25, 2017
    Applicant: Exosomics Siena S.p.A.
    Inventors: Francesco LOZUPONE, Antonio Chiesi, Paolo Guazzi, Natasa Zarovni, Pietro Ferruzzi, Davide Zocco