Patents Assigned to Expression Diagnostics, Inc.
  • Patent number: 7579148
    Abstract: Methods of diagnosing or monitoring an autoimmune or chronic inflammatory disease, particularly SLE in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring chronic inflammatory disease, particularly SLE infection and kits or systems containing the same are also described.
    Type: Grant
    Filed: November 15, 2004
    Date of Patent: August 25, 2009
    Assignee: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Publication number: 20070248978
    Abstract: The invention relates to methods useful for diagnosing and monitoring the steroid responsiveness of a subject by detecting expression of steroid modulated genes and for predicting transplant rejection and non-rejection.
    Type: Application
    Filed: April 9, 2007
    Publication date: October 25, 2007
    Applicant: Expression Diagnostics, Inc.
    Inventors: Preeti Lal, Steven Rosenberg, Tod Klinger
  • Patent number: 7235358
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: June 26, 2007
    Assignee: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice
  • Publication number: 20070037167
    Abstract: Methods of diagnosing or monitoring an autoimmune or chronic inflammatory disease, particularly SLE in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring chronic inflammatory disease, particularly SLE infection and kits or systems containing the same are also described.
    Type: Application
    Filed: November 15, 2004
    Publication date: February 15, 2007
    Applicant: EXPRESSION DIAGNOSTICS, INC.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Publication number: 20070037166
    Abstract: Methods of diagnosing or monitoring transplant rejection or cytomegalovirus infection in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection or cytomegalovirus infection and kits or systems containing the same are also described.
    Type: Application
    Filed: November 15, 2004
    Publication date: February 15, 2007
    Applicant: EXPRESSION DIAGNOSTICS, INC.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Publication number: 20060263813
    Abstract: Methods useful in monitoring the functional status of a transplant in a patient by detecting the expression levels of gene panels are described herein. Algorithms for analysis of the expression for monitoring the functional status of transplants are also described.
    Type: Application
    Filed: May 11, 2006
    Publication date: November 23, 2006
    Applicant: EXPRESSION DIAGNOSTICS, INC.
    Inventors: Steven Rosenberg, Preeti Lal, Kirk Fry, Tod Klingler, Dirk Walther, Robert Woodward
  • Patent number: 7026121
    Abstract: Methods of diagnosing or monitoring transplant rejection or cytomegalovirus infection in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection or cytomegalovirus infection and kits or systems containing the same are also described.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: April 11, 2006
    Assignee: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly
  • Publication number: 20060051803
    Abstract: Described herein is a system for monitoring gene expression for diagnosing and monitoring inflammation disorders, and for monitoring gene expression in inflammation disorders in response to a particular drug treatment reginmen. This system for detecting nucleic acid expression in a body fluid uses an isolated polynucleotide to detect expression of a nucleic acid comprising a nucleotide sequence selected from the group consisting of SEQ ID NO: 5; SEQ ID NO:11; SEQ ID NO:17; and SEQ ID NO: 23. These nucleic acids are differentially expressed in body fluid in an individual with a disease criterion for a disease as listed in Table 1 as compared to an individual without the disease criterion.
    Type: Application
    Filed: September 8, 2005
    Publication date: March 9, 2006
    Applicant: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Darren Tayama, Dirk Walther, Preeti Lal
  • Patent number: 6905827
    Abstract: Methods of diagnosing or monitoring an autoimmune or chronic inflammatory disease, particularly SLE in a patient by detecting the expression level of one or more genes or surrogates derived therefrom in the patient are described. Diagnostic oligonucleotides for diagnosing or monitoring chronic inflammatory disease, particularly SLE infection and kits or systems containing the same are also described.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: June 14, 2005
    Assignee: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly