Patents Assigned to Expression Genetics
  • Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
    Patent number: 6652886
    Abstract: A biodegradable, novel cationic coopolymer comprising a a poly(alkylenimine)(PAI), a hydrophilic polymer, and a biodegradable linker, wherein the biodegradable linker covalently links the PAI and the hydrophilic polymer. The biodegradable cationic copolymers in the present invention can be used in drug delivery and are especially useful for delivery of a nucleic acid or any anionic bioactive agent to various organs and tissues after local or systemic administration.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: November 25, 2003
    Assignee: Expression Genetics
    Inventors: Cheol Hee Ahn, Sung Wan Kim