Patents Assigned to Expression Therapeutics, LLC.
  • Nucleic acid and amino acid sequences encoding high-level expressor factor VIII polypeptides and methods of use
    Patent number: 7635763
    Abstract: Methods and compositions are provided that allow for high-level expression of a factor VIII polypeptide. More specifically, methods and compositions are provided comprising nucleic acid and amino acid sequences comprising a modified factor VIII that result in high-level expression of the polypeptide. The methods and compositions of the invention find use in the treatment of factor VIII deficiency including, for example, hemophilia A.
    Type: Grant
    Filed: March 30, 2004
    Date of Patent: December 22, 2009
    Assignee: Expression Therapeutics, LLC.
    Inventor: John S. Lollar