Patents Assigned to EXTEND BIOSCIENCES, INC.
  • RNAi VITAMIN D CONJUGATES
    Publication number: 20160114049
    Abstract: The invention provides non-hormonal vitamin D conjugated to therapeutic RNA compounds that result in the compounds having increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. The vitamin D targeting groups are coupled to the therapeutic RNA compounds via the third carbon on the vitamin D backbone.
    Type: Application
    Filed: October 21, 2015
    Publication date: April 28, 2016
    Applicant: EXTEND BIOSCIENCES, INC.
    Inventors: Tarik Soliman, Laura M. Hales, Daniel B. Hall, Howard P. Sard, Vishnumurthy Hegde
  • INSULIN VITAMIN D CONJUGATES
    Publication number: 20160114001
    Abstract: The invention provides non-hormonal vitamin D conjugated to insulin peptides that result in the peptides having increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. The vitamin D targeting groups are coupled to the insulin peptides via the third carbon on the vitamin D backbone.
    Type: Application
    Filed: October 21, 2015
    Publication date: April 28, 2016
    Applicant: EXTEND BIOSCIENCES, INC.
    Inventors: Tarik Soliman, Laura M. Hales, Daniel B. Hall, Howard Sard, Vishnumurthy Hegde
  • THERAPEUTIC VITAMIN D CONJUGATES
    Publication number: 20160113993
    Abstract: The invention provides non-hormonal vitamin D conjugated to apelin proteins that result in increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. In some embodiments, the vitamin D targeting groups are coupled to the apelin proteins via the third carbon on the vitamin D backbone.
    Type: Application
    Filed: October 21, 2015
    Publication date: April 28, 2016
    Applicant: EXTEND BIOSCIENCES, INC.
    Inventors: Tarik Soliman, Laura M. Hales, Daniel B. Hall, Christopher So, Howard P. Sard, Vishnumurthy Hegde
  • VITAMIN D-GHRELIN CONJUGATES
    Publication number: 20150065420
    Abstract: The invention provides carriers that enhance the absorption, half-life or bioavailability of Ghrelin peptides. The carriers comprise targeting groups that bind the Vitamin D Binding protein (DBP), conjugation groups for coupling the targeting groups to the therapeutic compounds, and optionally scaffolding moieties.
    Type: Application
    Filed: November 15, 2014
    Publication date: March 5, 2015
    Applicant: EXTEND BIOSCIENCES, INC.
    Inventors: Tarik Soliman, Laura M. Hales, Howard P. Sard, Mukkanti Amere