Patents Assigned to Eyegene, Inc.
  • Vaccine for inducing an improved immune reaction
    Patent number: 9572877
    Abstract: The present invention relates to a pharmaceutical vaccine composition comprising: (a) a pathogen-derived antigen selected from the group consisting of Mycobacterium tuberculosis antigen, Bacillus anthracis antigen, HAV (hepatitis A virus) antigen, HBV (hepatitis B virus) antigen, HCV (hepatitis C virus) antigen, HIV (human immunodeficiency virus) antigen, influenza virus antigen, HSV (herpes simplex virus) antigen, Hib (Haemophilus influenzae type b) antigen, Neisseria meningitidis antigen, Corynebacterium diphtheriae antigen, Bordetella pertussis antigen, Clostridium tetani antigen and Varicella virus antigen; (b) a deacylated non-toxic LOS (lipooligosaccharide); and (c) a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: December 17, 2011
    Date of Patent: February 21, 2017
    Assignee: EYEGENE, INC.
    Inventors: Yang Je Cho, Na Gyong Lee, Jin Wook Jang, Kwang Sung Kim, Won II Yoo
  • Pharmaceutical composition for preventing or treating arteriosclerosis
    Patent number: 9290542
    Abstract: The present invention provides a pharmaceutical composition for preventing or treating arteriosclerosis, comprising: a pharmaceutically effective amount of a protein comprising the amino acid sequence of SEQ ID NO: 1; and a pharmaceutically acceptable carrier. The composition of the present invention exhibits no toxicity in the liver or kidney and effectively reduces the formation of atherosclerotic plaques, thereby exhibiting efficacy in treating arteriosclerosis.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: March 22, 2016
    Assignee: EYEGENE, INC.
    Inventors: Yang Je Cho, Jin Wook Jang, Hyeong Joon Lim
  • METHOD FOR TREATING VASCULAR-RELATED DISEASE
    Publication number: 20140105868
    Abstract: A method for treating a vascular-related disease in a subject in need thereof, includes administering to the subject a peptide having a sequence Xaa-Gly-Asp. The peptide may have a sequence of SEQ ID NOS: 1, 2, 4, 6 to 10. The vascular-related disease may be edema and/or ischemia caused by blood leakage of blood vessel walls, damages of blood vessels or abnormal angiogenesis.
    Type: Application
    Filed: October 2, 2013
    Publication date: April 17, 2014
    Applicant: EYEGENE, INC.
    Inventors: Doo-Sik KIM, Yang-Je CHO, Won-Il YOO, Oh-Woong KWON, Jin-Wook JANG, Hyeong-Joon LIM, Soo-Mee KWON
  • VACCINE FOR INDUCING AN IMPROVED IMMUNE REACTION
    Publication number: 20130273101
    Abstract: The present invention relates to a pharmaceutical vaccine composition comprising: (a) a pathogen-derived antigen selected from the group consisting of Mycobacterium tuberculosis antigen, Bacillus anthracis antigen, HAV (hepatitis A virus) antigen, HBV (hepatitis B virus) antigen, HCV (hepatitis C virus) antigen, HIV (human immunodeficiency virus) antigen, influenza virus antigen, HSV (herpes simplex virus) antigen, Hib (Haemophilus influenzae type b) antigen, Neisseria meningitidis antigen, Corynebacterium diphtheriae antigen, Bordetella pertussis antigen, Clostridium tetani antigen and Varicella virus antigen; (b) a deacylated non-toxic LOS (lipooligosaccharide); and (c) a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 17, 2011
    Publication date: October 17, 2013
    Applicant: EYEGENE, INC.
    Inventors: Yang Je Cho, Na Gyong Lee, Jin Wook Jang, Kwang Sung Kim, Won Il Yoo
  • Composition for treating retinopathy or glaucoma comprising thrombin derived peptides
    Patent number: 8372811
    Abstract: Disclosed is a composition for treating retinopathy comprising thrombin derived peptide as an effective component.
    Type: Grant
    Filed: September 21, 2007
    Date of Patent: February 12, 2013
    Assignee: Eyegene, Inc.
    Inventors: Jin Wook Jang, Hyeong Joon Lim, Yang Je Cho, Won Il Yoo, Doo Sik Kim, Oh Woong Kwon, Kyoung Chul Ko, Kyung Sul Kim
  • Composition for Treating Retinopathy or Glaucoma Comprising Thrombin Derived Peptides
    Publication number: 20100297100
    Abstract: Disclosed is a composition for treating retinopathy comprising thrombin derived peptide as an effective component.
    Type: Application
    Filed: September 21, 2007
    Publication date: November 25, 2010
    Applicant: Eyegene, Inc.
    Inventors: Jin-Wook Jang, Hyeong-Joon Lim, Yang-Je Cho, Won-Il Yoo, Doo-Sik Kim, Oh-Woong Kwon, Kyoung-Chul Ko, Kyung-Sul Kim
  • Immune stimulating and controlling composition comprising bacterial chromosomal DNA fragments and non-toxic lipopolysaccharides
    Patent number: 7507802
    Abstract: The present invention relates to immune stimulating and controlling composition comprising bacterial chromosomal DNA fragments and non-toxic lipopolysacchararides. The composition of the present invention can be industrially applied the effective materials for treating cancers and adjuvant.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: March 24, 2009
    Assignee: Eyegene, Inc.
    Inventors: Bo Young Ahn, Yang Je Cho, Won Il Yoo, Sung Ho Lee, Hye Ran Park, Dong Hyun Lee, Na-Gyong Lee, Doo Sik Kim
  • Polypeptide Inducing the Secretion of Angiopoietin
    Publication number: 20080009441
    Abstract: This invention relates to Cell supernatant protein for inducing angiogenesis-1 secretion. The protein of the invention can be useful as therapeutic agent for angiogenesis-related diseases.
    Type: Application
    Filed: March 31, 2004
    Publication date: January 10, 2008
    Applicant: EYEGENE, INC.
    Inventors: Yang-Je Cho, Bo-Young Ahn, Doo-Sik Kim, Won-Il Yoo