Abstract: The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.
Type:
Grant
Filed:
February 6, 2018
Date of Patent:
August 4, 2020
Assignee:
Eyeon Particle Sciences LLC
Inventors:
Eugene Rex Cooper, David Maxwell Kleinman, Andrew Loxley, Mark A. Mitchnick
Abstract: The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.
Type:
Grant
Filed:
March 14, 2016
Date of Patent:
February 6, 2018
Assignee:
Eyeon Particle Sciences LLC
Inventors:
Eugene Rex Cooper, David Maxwell Kleinman, Andrew Loxley, Mark A. Mitchnick
Abstract: The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.
Type:
Grant
Filed:
July 10, 2014
Date of Patent:
March 29, 2016
Assignee:
Eyeon Particle Sciences LLC
Inventors:
Eugene Rex Cooper, David Maxwell Kleinman, Andrew Loxley, Mark Mitchnick
Abstract: The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.
Type:
Grant
Filed:
March 18, 2015
Date of Patent:
March 15, 2016
Assignee:
EYEON PARTICLE SCIENCES LLC
Inventors:
Eugene Rex Cooper, David Maxwell Kleinman, Andrew Loxley, Mark Mitchnick
Abstract: The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.
Type:
Grant
Filed:
July 10, 2014
Date of Patent:
April 14, 2015
Assignee:
Eyeon Particle Sciences LLC
Inventors:
Eugene Rex Cooper, David Maxwell Kleinman, Andrew Loxley, Mark Mitchnick
Abstract: The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.
Type:
Grant
Filed:
February 18, 2010
Date of Patent:
August 12, 2014
Assignee:
Eyeon Particle Sciences LLC
Inventors:
Eugene R. Cooper, David M. Kleinman, Andrew Loxley, Mark Mitchnick
Abstract: The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.
Type:
Application
Filed:
February 18, 2010
Publication date:
September 9, 2010
Applicant:
Eyeon Particle Sciences LLC
Inventors:
Eugene R. Cooper, David M. Kleinman, Andrew Loxley, Mark Mitchnick