Abstract: Provided herein are balloon systems and related methods for the treatment of obesity. The system includes a trans-abdominal gastric cannula and size-varying balloons that, with the assistance of the cannula(s) and anchors, are specially positioned and anchored to the gastric wall. The size-varying balloon may have an annulus that in combination with reliable and precise balloon positioning, minimizes the risk of gastric obstruction during use. A malabsorption sleeve may be positioned in the small intestine to further restrict caloric intake through the small intestine. The specially-configured gastric cannula provides a platform for accessing the gastric environment that facilitates precise handling, manipulation, and placement of balloons, including an annular-shaped balloon, in the gastric environment, including by balloon anchors connecting the balloon wall to the lumen-facing stomach wall.

Abstract: The present disclosure relates generally to prosthetic devices for use in restricting food and caloric intake into the stomach and of absorption of the food components in the stomach and small intestine. The system includes an elongated bariatric sleeve having a normally superior or upper proximal end and a normally inferior or lower distal end. An elongated lumen support member is positioned within the first lumen in contacting relation with the first membrane for maintaining the first lumen in an open position. A proximal anchor ring with a central aperture and a catheter channel is connected to the proximal end of the sleeve to the collar member. The anchor is inflatable or expandable memory material for anchoring the sleeve in superior relation to a pyloric valve of the patient's stomach. An anchor weight is connected to the distal end of the first flexible tube.