Patents Assigned to F-STAR BETA LIMITED
  • FC BINDING FRAGMENTS COMPRISING A PD-L1 ANTIGEN-BINDING SITE
    Publication number: 20210139590
    Abstract: The application relates to specific binding members which bind to programmed death-ligand (PD-L1). The specific binding members preferably comprise a PD-L1 antigen-binding site located in structural loops of a constant domain of the specific binding member. The specific binding members find application, for example, in the treatment of cancer, as well as infectious diseases, inflammation, diseases and conditions associated with inflammation, and inflammatory diseases.
    Type: Application
    Filed: December 19, 2018
    Publication date: May 13, 2021
    Applicant: F-STAR BETA LIMITED
    Inventors: Mihriban Tuna, Francisca Wollerton Van Horck, Ryan Fiehler, Mustapha Faroudi, Frederick Akele, Fadi Badr, Cyril Privezentzev
  • LAG-3 BINDING MEMBERS
    Publication number: 20190330344
    Abstract: The present invention relates to specific binding members which bind to lymphocyte-activation gene 3 (LAG-3). The specific binding members preferably comprise a LAG-3 antigen-binding site which may be located in two or more structural loops of a CH3 domain of the specific binding member. The specific binding members of the invention find application, for example, in cancer therapy.
    Type: Application
    Filed: June 20, 2017
    Publication date: October 31, 2019
    Applicant: F-STAR BETA LIMITED
    Inventors: Mihriban Tuna, Francisca Wollerton Van Horck, Katy Louise Everett, Miguel Gaspar, Matthew Kraman, Katarzyna Kmiecik, Natalie Fosh
  • EGFR BINDING MOLECULES
    Publication number: 20190202920
    Abstract: The application relates to specific binding members which bind the human epidermal growth factor receptor (EGFR). The specific binding members preferably comprise an EGFR antigen-binding site which may be located in two or more structural loops of a CH3 domain of the specific binding member. The specific binding members are expected to find application in the treatment of cancers expressing EGFR.
    Type: Application
    Filed: July 19, 2017
    Publication date: July 4, 2019
    Applicant: F-STAR BETA LIMITED
    Inventors: Mihriban TUNA, Kin-Mei LEUNG, Haijun SUN, Melanie MEDCALF, Samine ISAAC