Patents Assigned to Fabrica Espanola de Productos Quimicos y Farmaceuticos S.A. (FAES)
  • Patent number: 5877187
    Abstract: New benzimidazole derivatives of formula: ##STR1## in which R.sub.1 is H or a short chain hydrocarbon group such as methyl, hyl, isopropyl, cyclopropyl, vinyl, etc., and R.sub.2 is a group selected from among the following: CH.sub.2 OH, COOH, COOR.sub.3 and 4,4-dimethyl-2-oxazolinyl, R.sub.3 being a short chain alkyl group such as methyl, ethyl, etc., are described.A description is also made of the preparation of these compounds, which have a high H.sub.1 antihistaminic and antiallergic activity and are devoid of effects on the central nervous and cardiovascular systems.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: March 2, 1999
    Assignee: Fabrica Espanola de Productos Quimicos y Farmaceuticos S.A. (FAES)
    Inventors: Aurelio Orjales, Victor Rubio, Maravillas Bordell