Patents Assigned to Fabrus, Inc.
  • Anti-DLL4 antibodies and uses thereof
    Patent number: 9403904
    Abstract: Provided herein are anti-DLL4 antibodies and methods of using anti-DLL4 antibodies as therapeutic agents in diseases or disorders associated with DLL4.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: August 2, 2016
    Assignee: Fabrus, Inc.
    Inventors: Vaughn Smider, Helen Hongyuan Mao, Cornelia Bentley, Tyson Chase
  • ANTIBODIES WITH ULTRALONG COMPLEMENTARITY DETERMINING REGIONS
    Publication number: 20160168231
    Abstract: The present disclosure provides antibodies, including antibodies comprising ultralong CDR3 and uses thereof.
    Type: Application
    Filed: July 18, 2014
    Publication date: June 16, 2016
    Applicant: Fabrus, Inc.
    Inventors: Miguel DE LOS RIOS, Omar BAZIRGAN
  • Combinatorial antibody libraries and uses thereof
    Patent number: 9221902
    Abstract: Methods for making a combinatorial antibody library from human germline segments are provided. Also provided are libraries of nucleic acid molecules compiled from germline segments encoding VL chains and libraries of nucleic acid molecules encoding VH chains, and resulting antibody libraries. The libraries are provided as addressable libraries. Methods for screening antibody libraries against a target protein antigen, and the identified or selected antibodies are provided.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: December 29, 2015
    Assignee: Fabrus, Inc.
    Inventors: Vaughn Smider, James Graziano, Helen Hongyuan Mao, Byeong Doo Song, Tyson Chase, Omar Bazirgan