Patents Assigned to Factor Bioscience Inc.
-
Patent number: 10662410Abstract: The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic acids, methods, kits, and devices for inducing cells to express proteins, methods, kits, and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods for inducing cells to express proteins and for reprogramming and gene-editing cells using RNA are disclosed. Methods for producing cells from patient samples, cells produced using these methods, and therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: January 30, 2020Date of Patent: May 26, 2020Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 10611722Abstract: The present invention relates in part to novel cationic lipids and their use, e.g., in delivering nucleic acids to cells.Type: GrantFiled: October 22, 2019Date of Patent: April 7, 2020Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Franklin Kostas, Christopher Rohde
-
Patent number: 10590437Abstract: The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.Type: GrantFiled: July 26, 2019Date of Patent: March 17, 2020Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 10576167Abstract: The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic acids to cells, tissues, organs, and patients, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these methods, kits, and devices.Type: GrantFiled: August 17, 2017Date of Patent: March 3, 2020Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 10556855Abstract: The present invention relates in part to novel cationic lipids and their use, e.g., in delivering nucleic acids to cells.Type: GrantFiled: October 22, 2019Date of Patent: February 11, 2020Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Franklin Kostas, Christopher Rohde
-
Patent number: 10501404Abstract: The present invention relates in part to novel cationic lipids and their use, e.g., in delivering nucleic acids to cells.Type: GrantFiled: July 30, 2019Date of Patent: December 10, 2019Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Franklin Kostas, Christopher Rohde
-
Patent number: 10472611Abstract: The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic acids, methods, kits, and devices for inducing cells to express proteins, methods, kits, and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods for inducing cells to express proteins and for reprogramming and gene-editing cells using RNA are disclosed. Methods for producing cells from patient samples, cells produced using these methods, and therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: May 2, 2019Date of Patent: November 12, 2019Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 10443045Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: April 3, 2019Date of Patent: October 15, 2019Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 10415060Abstract: The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.Type: GrantFiled: August 7, 2017Date of Patent: September 17, 2019Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 10369233Abstract: The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic acids to cells, tissues, organs, and patients, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these methods, kits, and devices.Type: GrantFiled: July 9, 2018Date of Patent: August 6, 2019Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 10363321Abstract: The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic acids to cells, tissues, organs, and patients, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these methods, kits, and devices.Type: GrantFiled: July 9, 2018Date of Patent: July 30, 2019Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 10350304Abstract: The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic acids to cells, tissues, organs, and patients, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these methods, kits, and devices.Type: GrantFiled: July 9, 2018Date of Patent: July 16, 2019Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 10301599Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: July 17, 2018Date of Patent: May 28, 2019Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Publication number: 20190008985Abstract: The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic acids to cells, tissues, organs, and patients, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these methods, kits, and devices.Type: ApplicationFiled: August 17, 2017Publication date: January 10, 2019Applicant: Factor Bioscience Inc.Inventors: Matthew ANGEL, Christopher ROHDE
-
Patent number: 9487768Abstract: The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.Type: GrantFiled: May 17, 2016Date of Patent: November 8, 2016Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 9127248Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: June 28, 2013Date of Patent: September 8, 2015Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
-
Publication number: 20130344602Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: ApplicationFiled: June 28, 2013Publication date: December 26, 2013Applicant: Factor Bioscience, Inc.Inventors: Matthew Angel, Christopher Rohde
-
Patent number: 8497124Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: May 7, 2012Date of Patent: July 30, 2013Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde