Abstract: The invention refers to a device for inhibiting the neural activity of a carotid sinus nerve (CSN) or carotid body of a subject, the device comprising: one or more transducers configured to apply a signal to the CSN or associated carotid body of the subject, optionally at least two such transducers; and a controller coupled to the one or more transducers, the controller controlling the signal to be applied by the one or more transducers, such that the signal inhibits the neural activity of the CSN or carotid body to produce a physiological response in the subject, wherein the physiological response is one or more of the group consisting of: an increase in insulin sensitivity in the subject, an increase in glucose tolerance in the subject, a decrease in (fasting) plasma glucose concentration in the subject, a reduction in subcutaneous fat content in the subject, and a reduction in obesity in the subject.
Type:
Application
Filed:
November 3, 2015
Publication date:
November 23, 2017
Applicants:
GALVANI BIOELECTRONICS LIMITED, FACULDADE DE CIÊNCIAS MÉDICAS DA UNIVERSIDADA NOVA DE LISBOA
Inventors:
Silvia Margarida Vilares Santos CONDE, Daniel John CHEW, Hans Jakob Kristoffer FAMM, Maria Pedro Sucena GUARINO, Brad HOLINSKI, Sonal PATEL