Abstract: The invention deals with the derivatives of benzilidine having basic formula as follows (I):
wherein X can be cyclohexanone, cyclopentanone, or acetone, while Y and Z can be either electron withdrawing, electron donating or steric group. Y may or may not be the same with Z. Methyl, ethyl, methoxy group or halogen were prefered in the experiment. The benzilidine cyclohexanone, benzilidine cyclopentanone, and benzilidine acetone derivates were found to be novel compounds showing anti-bacterial, antioxidant, and anti-inflammatory activities that enable them to be used for drug.
Type:
Grant
Filed:
February 20, 1998
Date of Patent:
April 1, 2003
Assignee:
Faculty of Pharmacy, The University of Gadjah Mada