Patents Assigned to FAKULTNI NEMOCNICE U SV. ANNY V BRNE
  • Nanodiamonds as artificial proteins for regulation of a cell signalling system
    Patent number: 11744855
    Abstract: Nanodiamonds having a positive ?-potential of at least 1 mV for use in sequestration of at least one FGF family member in organisms in vivo and in vitro. It has been found that nanodiamonds with a positive ?-potential show an extremely strong and selective binding to FGF family members, thus leading to their usability in the treatment of diseases related to aberrant FGF-FGFR signalling and/or interaction.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: September 5, 2023
    Assignees: USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I, MASARYKOVA UNIVERZITA, FAKULTNI NEMOCNICE U SV, ANNY V BRNE
    Inventors: Petr Cigler, Lukas Balek, Jan Havlik, Pavel Krejci, Lukas Trantirek, Silvie Trantirkova
  • NANODIAMONDS AS ARTIFICIAL PROTEINS FOR REGULATION OF A CELL SIGNALLING SYSTEM
    Publication number: 20210015856
    Abstract: Nanodiamonds having a positive ?-potential of at least 1 mV for use in sequestration of at least one FGF family member in organisms in vivo and in vitro. It has been found that nanodiamonds with a positive ?-potential show an extremely strong and selective binding to FGF family members, thus leading to their usability in the treatment of diseases related to aberrant FGF-FGFR signalling and/or interaction.
    Type: Application
    Filed: March 26, 2019
    Publication date: January 21, 2021
    Applicants: USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I., MASARYKOVA UNIVERZITA, FAKULTNI NEMOCNICE U SV. ANNY V BRNE
    Inventors: Petr CIGLER, Lukas BALEK, Jan HAVLIK, Pavel KREJCI, Lukas TRANTIREK, Silvie TRANTIRKOVA
  • Method of EKG signal processing and apparatus for performing the method
    Patent number: 9949655
    Abstract: A method of measuring and analyzing the ultra high frequency EKG is performed by measuring the EKG within the frequency range above 250 Hz with a dynamic range of at least 100 dB. In the UHF EKG signal positions of Rm of R wave in QRS complex of EKG are detected on the time axis and the EKG signal is converted to amplitude or power envelopes, the amplitude or power envelopes frequency range is anywhere within the limits from 0.2 Hz to at least 500 Hz. From these envelopes the amplitude and time numerical parameters that describe the myocardium depolarization inhomogeneity and electric myocardium dyssynchrony are determined, and these parameters are used for selecting the patients for multi-chamber stimulators implementation and optimization of their setting.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: April 24, 2018
    Assignees: USTAV PRISTROJOVE TECHNIKY AV CR, v.i.i., FAKULTNI NEMOCNICE U SV. ANNY V BRNE, M & I, SPOL. S.R.O.
    Inventors: Pavel Jurak, Josef Halamek, Vlastimil Vondra, Ivo Viscor, Petr Klimes, Filip Plesinger, Pavel Leinveber, Petr Vesely, Tereza Reichlova, Josef Sumbera, Jaroslav Meluzin, Karel Zeman, Miroslav Novak, Jolana Lipoldova, Michal Kuna