Patents Assigned to Farmatis, S.p.A.
  • Isoindoline derivative and a therapeutic composition thereof
    Patent number: 4338331
    Abstract: The patent is concerned with a new compound which is 1-methyl-2-(3'-sulphenyl-4'-chlorobenzamido)-isoindoline of formula: ##STR1## This compound, which is endowed with diuretic, salutaric and hypotensive activity, is prepared:(a) reacting .alpha.-methyl-.alpha.,.alpha.'-dibromo-o.xylene with t.butylcarbazate,(b) decomposing the thus obtained 1-methyl-N-(t.butyloxycarbonylamine)-isoindoline to the corresponding amino compound,(c) reacting the 1-methyl-2-amino-isoindoline hydrochloride with a halide of 4-chloro-sulphamido benzoic acid.
    Type: Grant
    Filed: January 9, 1981
    Date of Patent: July 6, 1982
    Assignee: Farmatis S.p.A.
    Inventor: Juan B. A. Scalesciani
  • Process for preparing 6-isobornyl-3,4-xylenol
    Patent number: 4239920
    Abstract: A process for preparing 6-isobornyl-3,4-xylenol by condensing camphene and 3,4-dimethylphenol benzylether in an inert anhydrous organic solvent in the presence of a Friedel-Crafts catalyst at a temperature of around 0.degree. C., and the 6-isobornyl-3,4-xylenol benzylether thus obtained is debenzylated by hydrogenating in the presence of a solvent and a hydrogenation catalyst.
    Type: Grant
    Filed: March 27, 1979
    Date of Patent: December 16, 1980
    Assignee: Farmatis, S.p.A.
    Inventor: Maria L. Del Conte