Patents Assigned to Farmington Pharma Development
  • Creatine prodrugs, compositions and methods of use thereof
    Patent number: 11407722
    Abstract: The invention describes membrane permeable creatine prodrugs, pharmaceutical compositions comprising membrane permeable creatine prodrugs, and methods of treating diseases such as ischemia, heart failure, neurodegenerative disorders and genetic disorders affecting the creatine kinase system comprising administering creatine prodrugs or pharmaceutical compositions thereof. The invention also describes treating a genetic disease affecting the creatine kinase system, such as, for example, a creatine transporter disorder or a creatine synthesis disorder comprising administering creatine prodrugs or pharmaceutical compositions thereof.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: August 9, 2022
    Assignee: FARMINGTON PHARMA DEVELOPMENT
    Inventor: William F. Brubaker
  • Creatine phosphate analog prodrugs, compositions and methods of use thereof
    Patent number: 11021501
    Abstract: The invention describes membrane permeable creatine phosphate analog prodrugs, pharmaceutical compositions comprising membrane permeable creatine phosphate analog prodrugs, and methods of treating diseases such as ischemia, heart failure, neurodegenerative disorders and genetic disorders affecting the creatine kinase system comprising administering creatine phosphate analog prodrugs or pharmaceutical compositions thereof. The invention also describes treating a genetic disease affecting the creatine kinase system, such as, for example, a creatine transporter disorder or a creatine synthesis disorder comprising administering creatine phosphate analog prodrugs or pharmaceutical compositions thereof.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: June 1, 2021
    Assignee: Farmington Pharma Development
    Inventor: William F. Brubaker
  • Creatine prodrugs, compositions and methods of use thereof
    Patent number: 10344007
    Abstract: The invention describes membrane permeable creatine prodrugs, pharmaceutical compositions comprising membrane permeable creatine prodrugs, and methods of treating diseases such as ischemia, heart failure, neurodegenerative disorders and genetic disorders affecting the creatine kinase system comprising administering creatine prodrugs or pharmaceutical compositions thereof. The invention also describes treating a genetic disease affecting the creatine kinase system, such as, for example, a creatine transporter disorder or a creatine synthesis disorder comprising administering creatine prodrugs or pharmaceutical compositions thereof.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: July 9, 2019
    Assignee: FARMINGTON PHARMA DEVELOPMENT
    Inventor: William F. Brubaker
  • Creatine prodrugs, compositions and methods of use thereof
    Patent number: 9617230
    Abstract: The invention describes membrane permeable creatine prodrugs, pharmaceutical compositions comprising membrane permeable creatine prodrugs, and methods of treating diseases such as ischemia, heart failure, neurodegenerative disorders and genetic disorders affecting the creatine kinase system comprising administering creatine prodrugs or pharmaceutical compositions thereof. The invention also describes treating a genetic disease affecting the creatine kinase system, such as, for example, a creatine transporter disorder or a creatine synthesis disorder comprising administering creatine prodrugs or pharmaceutical compositions thereof.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: April 11, 2017
    Assignee: FARMINGTON PHARMA DEVELOPMENT
    Inventor: William F. Brubaker
  • CREATINE PRODRUGS, COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20160176829
    Abstract: The invention describes membrane permeable creatine prodrugs, pharmaceutical compositions comprising membrane permeable creatine prodrugs, and methods of treating diseases such as ischemia, heart failure, neurodegenerative disorders and genetic disorders affecting the creatine kinase system comprising administering creatine prodrugs or pharmaceutical compositions thereof. The invention also describes treating a genetic disease affecting the creatine kinase system, such as, for example, a creatine transporter disorder or a creatine synthesis disorder comprising administering creatine prodrugs or pharmaceutical compositions thereof.
    Type: Application
    Filed: December 21, 2015
    Publication date: June 23, 2016
    Applicant: Farmington Pharma Development
    Inventor: William F. Brubaker