Patents Assigned to FDC Limited
  • 1-substituted, 4-(substituted phenoxymethyl)-1,2,3-triazole compounds with antifungal properties and methods for preparation thereof
    Patent number: 9540350
    Abstract: Disclosed herein are novel antifungal compounds of Formula 1, containing 1-substituted, 4-(substituted phenoxy-methyl)-1,2,3-triazole moieties coupled to a core having triazole ring, (un)substituted phenyl ring and tertiary alcoholic functionality, and pharmaceutically acceptable salts thereof; methods for preparing these compounds; and pharmaceutical preparations containing these novel compounds for prevention and treatment of fungal infections.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: January 10, 2017
    Assignees: FDC Limited, Council of Scientific & Industrial Research
    Inventors: Hanumant Bapurao Borate, Ananda Shahaji Kudale, Subhash Prataprao Chavan, Sunita Sharad Kunte, Mohan Anand Chandavarkar, Ramkrishnan Ramachandran Iyer, Amit Chandrakant Tawte, Deepali Damodar Rao
  • Optically active fluconazole analogues containing thiophenes as antifungal agents
    Patent number: 9447082
    Abstract: The invention discloses optically active compounds of Formula (1a) or Formula (1b), wherein R1 and R2 are independently selected from the group consisting of hydrogen and a halogen selected from the group consisting of fluorine, chlorine, bromine, and iodine; and wherein (a) R3 and R4 are independently selected from the group consisting of hydrogen and an alkyl group having a linear or branched chain having 1 to 20 carbon atoms, or (b) R3 and R4 together form a cycloalkyl ring having 3 to 10 carbon atoms fused to the thiophene ring; and wherein R5 is CN or COOR?, where R? is methyl or ethyl. The compounds of Formula (1a) or Formula (1b) may be used in pharmaceutical compositions for treating fungal infections.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: September 20, 2016
    Assignees: FDC Limited, Council of Scientific Industrial Research
    Inventors: Hanumant Bapurao Borate, Sangeshwer Prabhakar Sawargave, Subhash Prataprao Chavan, Mohan Anand Chandavarkar, Ramakrishnan Ramacahndran Iyer, Amit Chandrakant Tawte, Deepali Damodar Rao
  • Enantiomers of fluconazole analogues containing thieno-[2,-3-D]pyrimidin-4(3H)-one moiety as antifungal agents
    Patent number: 9181269
    Abstract: The present invention discloses novel enantiomeric antifungal compounds of Formula (1a) and Formula (1b) containing thieno-[2,3-d]Jpyrimidin-4(3H)-one moiety and pharmaceutically acceptable salts thereof, method of preparing these compounds, the use of these compounds in prevention and treatment of fungal infections, and pharmaceutical preparations containing these compounds.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: November 10, 2015
    Assignees: FDC Limited, Council for Scientific & Industrial Research
    Inventors: Hanumant Bapurao Borate, Suleman Riyajsaheb Maujan, Sangmeshwer Prabhkara Sawargave, Subhash Prataprao Chavan, Mohan Anand Chandavarkar, Ramkrishnan Ramachandran Iyer, Vikas Vasant Nawathye, Gajanan Jalindar Chavan, Amit Chandrakant Tawte, Deepali Damodar Rao
  • Thieno[2,3-D]-pyrimidin-4(3)-one compounds with antifungal properties and process thereof
    Patent number: 8324227
    Abstract: The present invention discloses novel compounds of the Formula (1), containing thieno-[2,3-d]pyrimidin-4(3H)-one moieties and pharmaceutically acceptable salts thereof, methods for preparing these compounds, the use of these compounds in prevention and treatment of fungal infections, and pharmaceutical preparations containing these novel compounds.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: December 4, 2012
    Assignee: FDC Limited
    Inventors: Hanumant Bapurao Borate, Suleman Riyajsaheb Maujan, Sangmesher Prabhakar Sawargave, Sheerang Vidhyadhar Joshi, Sharangi Vaiude, Mohan Anand Chandavarkar
  • Thiopene containing analogues of fluconazole as antifungal agents and process for their preparation
    Patent number: 8236840
    Abstract: The present invention discloses novel compounds of the Formula (1), containing thiophene moieties and pharmaceutically acceptable salts thereof, methods for preparing these compounds, the use of these compounds in prevention and treatment of fungal infections, and pharmaceutical preparations containing these novel compounds.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: August 7, 2012
    Assignees: Council of Scientific & Industrial Research, FDC Limited
    Inventors: Hanumant Bapurao Borate, Sangmeshwer Prabhakar Sawargave, Suleman Riyajsaheb Maujan, Mohan Anand Chandavarkar, Sharangi Ravinda Vaiude, Vinay Anant Joshi
  • NOVEL USE OF AN INDICATOR CELL LINE FOR BIOASSAY
    Publication number: 20090197293
    Abstract: The present invention relates to methods of bioassay for detecting the effective concentration of Granulocyte Colony Stimulating Factor (G-CSF), and estimating ED50 and specific activity of G-CSF using a human acute myeloid cell line. The invention also relates to use of this technique for estimating the potency of G-CSF samples during various stages of a purification process.
    Type: Application
    Filed: August 20, 2008
    Publication date: August 6, 2009
    Applicant: FDC Limited
    Inventors: Nandan M. CHANDAVARKAR, Amit C. TAWTE, Anagha A. SHIRKE, Mariamma A. PARACKAL