Patents Assigned to febit biotech GmbH
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Publication number: 20100029008Abstract: The present invention concerns methods of polymerase independent template directed elongation of polynucleotides, nucleotide building blocks used in these methods as well as the use of the methods and building blocks for the determination of nucleotide sequences, in particular for the determination of SNPs, base modifications, mutations, rearrangements and methylation patterns.Type: ApplicationFiled: December 12, 2005Publication date: February 4, 2010Applicant: FEBIT BIOTECH GMBHInventors: Jan André Rojas Stütz, Eric Kervio, Clemens Richert, Patrizia Hagenbuch, Annette Hochgesand, Niels Griesang, Stephanie Vogel, Ulrich Plutowski
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Publication number: 20100015668Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.Type: ApplicationFiled: August 23, 2007Publication date: January 21, 2010Applicant: Febit Biotech GmbHInventors: Peer Staehler, Raphael Carapito
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Publication number: 20080132430Abstract: The present invention relates to a microfluid reaction carrier intended for the purely fluid or light-controlled synthesis or analysis of oligomers or polymers. The reaction carrier comprises a structure of flow channels for the fluids, while supply channels and discharge channels parallel to the latter form an angle relative to the plane of the structure of the flow channels (reaction areas).Type: ApplicationFiled: January 2, 2008Publication date: June 5, 2008Applicant: Febit Biotech GmbHInventors: Cord Fredrich Stahler, Manfred Muller, Peer Friedrich Stahler, Ralf (Peter) Mauritz
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Patent number: 7361314Abstract: The present invention relates to a microfluid reaction carrier intended for the purely fluid or light-controlled synthesis or analysis of oligomers or polymers. The reaction carrier comprises a structure of flow channels for the fluids, while supply channels and discharge channels parallel to the latter form an angle relative to the plane of the structure of the flow channels (reaction areas).Type: GrantFiled: August 1, 2000Date of Patent: April 22, 2008Assignee: febit biotech GmbHInventors: Cord Fredrich Stähler, Manfred Müller, Peer Friedrich Stähler, Ralf Mauritz
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Patent number: 7226862Abstract: In the case of a method for producing a fluid device with a fluid structure having an active height, a basic wafer is provided, which comprises a supporting substrate, an insulating layer on the supporting substrate and a patterned layer on the supporting substrate, the thickness of the patterned layer determining the active height of the fluid structure. Following this, the fluid structure is produced in the patterned layer of the basic wafer, said fluid structure extending through the semiconductor layer. A transparent wafer is then applied so that the fluid structure is covered. Subsequently, the supporting substrate and the insulating layer are removed from the back so that the fluid structure is exposed at a second surface of the patterned layer. Finally, a second transparent wafer is attached to the exposed second surface of the semiconductor layer so that the fluid structure is covered. The essential parameter of the fluid device, viz.Type: GrantFiled: June 4, 2001Date of Patent: June 5, 2007Assignee: Febit Biotech GmbHInventors: Cord F. Staehler, Tilo Strobelt, Johannes Frech, Peter Nommensen, Martin Mueller
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Publication number: 20070087349Abstract: The invention relates to a template-based method for preparing nucleic acid double strands.Type: ApplicationFiled: November 18, 2004Publication date: April 19, 2007Applicant: Febit Biotech GmbHInventors: Peer Staehler, Cord Stahler, Markus Beier
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Publication number: 20070031877Abstract: A method for producing a support for determining analytes. The method comprises the steps of (a) providing a support comprising at least one channel, comprising a conduit having an intake and an outlet for passing fluid from the intake to the outlet, in the support body, (b) passing liquid with building blocks for synthesizing polymeric receptors through the channel or channels of the support body, (c) site- and/or time-specifically immobilizing the receptor building blocks in each case on predetermined positions in the channel or channels by illumination and (d) repeating steps (b) and (c) until the required receptors have been synthesized in each case on the predetermined positions.Type: ApplicationFiled: August 28, 2006Publication date: February 8, 2007Applicant: febit biotech GmbHInventors: Cord Stahler, Peer Stahler, Manfred Muller, Fritz Stahler, Hans Lindner
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Publication number: 20060292612Abstract: The invention relates to a method which can be used to test firstly a reaction and secondly the distribution of functional groups on a surface. This method is employed in a situation that demands documentation or testing of a distribution of surface functionalization, which is as homogeneous as possible.Type: ApplicationFiled: June 14, 2006Publication date: December 28, 2006Applicant: febit biotech GmbHInventor: Matthias Scheffler
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Patent number: 7097974Abstract: A method for producing a support for determining analytes. The method comprises the steps of (a) providing a support comprising at least one channel, comprising a conduit having an intake and an outlet for passing fluid from the intake to the outlet, in the support body, (b) passing liquid with building blocks for synthesizing polymeric receptors through the channel or channels of the support body, (c) site- and/or time-specifically immobilizing the receptor building blocks in each case on predetermined positions in the channel or channels by illumination and (d) repeating steps (b) and (c) until the required receptors have been synthesized in each case on the predetermined positions.Type: GrantFiled: August 27, 1999Date of Patent: August 29, 2006Assignee: febit biotech GmbHInventors: Cord F. Stähler, Peer F. Stähler, Manfred Müller, Fritz Stähler, Hans Lindner
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Publication number: 20060111564Abstract: The present invention relates to a process for synthesizing biopolymers by stepwise assembly from protected synthesis building blocks which carry two-stage protective groups. The two-stage protective groups are activated by a first illumination step and eliminated by a subsequent chemical treatment step. Photoactivatable components which considerably speed up the activation process via intramolecular triplet sensitizers or/and have fluorescence properties are used. The two-stage protective groups can be used in particular within the framework of quality control.Type: ApplicationFiled: December 23, 2003Publication date: May 25, 2006Applicant: Febit biotech GmbH Im Neuenheimer Feld 515Inventors: Ramon Guimil, Matthias Scheffler, Barbro Beijer