Abstract: A method for disrupting a sample of biological material of human, animal, or plant origin for subsequent proteome analysis by a mass spectrometry method is provided. The method involves disrupting the sample by treatment with a certain volume of an organic acid until the sample completely dissolves, incubating the sample for a certain period, and then neutralizing the sample with a neutralizing solution until a pH value between 7 and 9 is reached.
Type:
Grant
Filed:
December 27, 2018
Date of Patent:
November 2, 2021
Assignee:
FEDERAL REPUBLIC OF GERMANY LAST REPRESENTED BY THE ROBERT-KOCH-INSTITUT WHICH IS REPRESENTED BY ITS PRESIDENT
Inventors:
Andy Schneider, Jörg Döllinger, Peter Lasch