Patents Assigned to Federalnoe Gosudarstvennoe Unitarnoe Predpriyatie Gosudarstvenny Nauchny Tsentr “Nauchno-Issledovatelsky Institut Organicheskikh Poluproduktov I Krasitelei” (FGUP GNTTS “Niopik”)
  • Method for therapy of liver tumors
    Patent number: 7220425
    Abstract: A method for regional administration of preparations during the therapy of liver tumor, comprising administering a preparation into a branch of the portal vein with the simultaneous occlusion of afferent and efferent lobe vessels (branches of the portal vein proximal the place of puncture, branches of the hepatic artery and lobar hepatic vein) for 5–15 minutes. During catalytic therapy, it is preferable to use Teraphtalum as the preparation and to administer ascorbic acid after termination of occlusion. During photodynamic therapy, it is preferable to use photosens as the preparation and to carry out irradiation of the tumor after 10–35 minutes. This method of administration provides for the predominant accumulation of the preparations in the target lobe (tumor carrier lobe) of the liver, their low penetration into the systemic blood flow, which makes it possible to reduce the dose of the preparation and its general toxicity.
    Type: Grant
    Filed: November 26, 2001
    Date of Patent: May 22, 2007
    Assignees: Federalnoe Gosudarstvennoe Unitarnoe Predpriyatie Gosudarstvenny Nauchny Tsentr “Nauchno-Issledovatelsky Institut Organicheskikh Poluproduktov I Krasitelei” (FGUP GNTTS “Niopik”), Gosudarstevennoe Obrazovatelnoe Uchrezhdenie Vysshego Professionalnogo Obrazovaniya Moskovskaya Meditsinskaya Akademiya IM. I.M. Sechenova RF (Gouvpo MMA IM. I.M. Sechenova MZ RF)
    Inventors: Georgy Nikolaevich Vorozhtsov, Eduard Izrailevich Galperin, Roman Sergeevich Goloschapov, Sergei Vitalievich Grachev, Tatyana Gennadievna Dyuzheva, Natalya Ivanovna Kazachkina, Oleg Leonidovich Kalia, Yury Mikhailovich Luzhkov, Evgeny Antonovich Lukyanets, Vadim Romanovich Nakhamiyaev