Abstract: Pharmaceutical combinations of LTV-17 (I), a lactivicin derivative, and ?-lactamase inhibitors are provided, wherein the combinations comprise antibacterial agents suitable for use in the treatment or prevention of bacterial infections.
Type:
Grant
Filed:
November 10, 2022
Date of Patent:
June 4, 2024
Assignee:
FEDORA PHARMACEUTICALS INC.
Inventors:
Sameeh M. Salama, Samarendra N. Maiti, Renata Jankowska
Abstract: Lactivicin compounds of formula (I) and pharmaceutically acceptable salts of the compounds of formula (I) are provided, wherein the compounds comprise antibiotics suitable for use either alone or in combination with ?-lactamase inhibitors and/or additional antibiotics (including ?-lactam and non-?-lactam antibiotics) in the treatment or prevention of bacterial infections.
Type:
Application
Filed:
July 25, 2023
Publication date:
November 23, 2023
Applicant:
FEDORA PHARMACEUTICALS INC.
Inventors:
Renata JANKOWSKA, Sameeh M. SALAMA, Samarendra N. MAITI
Abstract: Lactivicin compounds of formula (I) and pharmaceutically acceptable salts of the compounds of formula (I) are provided, wherein the compounds comprise antibiotics suitable for use either alone or in combination with ?-lactamase inhibitors and/or other antibiotics (including ?-lactam and non-?-lactam antibiotics) in the treatment or prevention of bacterial infections.
Type:
Grant
Filed:
March 29, 2022
Date of Patent:
October 10, 2023
Assignee:
FEDORA PHARMACEUTICALS INC.
Inventors:
Renata Jankowska, Sameeh M. Salama, Samarendra N. Maiti
Abstract: Pharmaceutical combinations of LTV-17 (I), a lactivicin derivative, and ?-lactamase inhibitors are provided, wherein the combinations comprise antibacterial agents suitable for use in the treatment or prevention of bacterial infections.
Type:
Application
Filed:
November 10, 2022
Publication date:
May 18, 2023
Applicant:
FEDORA PHARMACEUTICALS INC.
Inventors:
Sameeh M. SALAMA, Samarendra N. MAITI, Renata JANKOWSKA
Abstract: Lactivicin compounds of formula (I) and pharmaceutically acceptable salts of the compounds of formula (I) are provided, wherein the compounds comprise antibiotics suitable for use either alone or in combination with ?-lactamase inhibitors and/or other antibiotics (including ?-lactam and non-?-lactam antibiotics) in the treatment or prevention of bacterial infections.
Type:
Application
Filed:
March 29, 2022
Publication date:
October 13, 2022
Applicant:
FEDORA PHARMACEUTICALS INC.
Inventors:
Renata JANKOWSKA, Sameeh M. SALAMA, Samarendra N. MAITI
Abstract: The present invention relates to crystalline forms of a diazabicyclooctane derivative represented by Compound I, the process for producing the same and methods for using the same:
Abstract: The present invention relates to a pharmaceutical composition and a lyophilisate of a diazabicyclooctane derivative represented by Compound I, a process for producing the same and methods for using the same.
Abstract: The present invention relates to a process for producing crystalline and amorphous forms of a diazabicyclooctane derivative represented by Compound (I) and methods for producing the same.
Abstract: A compound of formula (I): wherein: M is hydrogen or a pharmaceutically acceptable salt-forming cation; Y is OR1 or NR2R3, and R1 ,R2, R3 and M are as defined herein. Also, methods of treating bacterial infection, pharmaceutical compositions, molecular complexes and processes for preparing compounds.
Type:
Grant
Filed:
June 28, 2018
Date of Patent:
January 28, 2020
Assignee:
FEDORA PHARMACEUTICALS INC.
Inventors:
Samarendra N. Maiti, Dai Nguyen, Jehangir Khan, Rong Ling
Abstract: A compound of formula (I): wherein: M is hydrogen or a pharmaceutically acceptable salt-forming cation; Y is OR1 or NR2R3, and R1 ,R2, R3 and M are as defined herein. Also, methods of treating bacterial infection, pharmaceutical compositions, molecular complexes and processes for preparing compounds.
Type:
Application
Filed:
June 28, 2018
Publication date:
October 25, 2018
Applicant:
FEDORA PHARMACEUTICALS INC.
Inventors:
Samarendra N. MAITI, Dai NGUYEN, Jehangir KHAN, Rong LING
Abstract: A compound of formula (I): wherein: M is hydrogen or a pharmaceutically acceptable salt-forming cation; Y is OR1 or NR2R3, and R1, R2, R3 and M are as defined herein. Also, methods of treating bacterial infection, pharmaceutical compositions, molecular complexes and processes for preparing compounds.
Type:
Grant
Filed:
June 2, 2016
Date of Patent:
July 24, 2018
Assignee:
FEDORA PHARMACEUTICALS INC.
Inventors:
Samarendra N. Maiti, Dai Nguyen, Jehangir Khan, Rong Ling
Abstract: New bicyclic compounds, their preparation, and their use as antibacterial agents, either alone or in combination with an antibiotic for the treatment of infections caused by ?-lactamase-producing pathogenic bacteria, are described.
Type:
Grant
Filed:
June 10, 2014
Date of Patent:
November 29, 2016
Assignee:
FEDORA PHARMACEUTICALS INC.
Inventors:
Samarendra N. Maiti, Dai Nguyen, Jehangir Khan, Rong Ling
Abstract: A compound of formula (I): wherein: M is hydrogen or a pharmaceutically acceptable salt-forming cation; Y is OR1 or NR2R3, and R1, R2, R3 and M are as defined herein. Also, methods of treating bacterial infection, pharmaceutical compositions, molecular complexes and processes for preparing compounds.
Type:
Application
Filed:
June 2, 2016
Publication date:
October 13, 2016
Applicant:
FEDORA PHARMACEUTICALS INC.
Inventors:
Samarendra N. MAITI, Dai NGUYEN, Jehangir KHAN, Rong LING
Abstract: A compound of formula (I): wherein: M is hydrogen or a pharmaceutically acceptable salt-forming cation; Y is OR1 or NR2R3, and R1, R2, R3 and M are as defined herein. Also, methods of treating bacterial infection, pharmaceutical compositions, molecular complexes and processes for preparing compounds.
Type:
Grant
Filed:
April 15, 2014
Date of Patent:
July 19, 2016
Assignee:
FEDORA PHARMACEUTICALS INC.
Inventors:
Samarendra N. Maiti, Dai Nguyen, Jehangir Khan, Rong Ling