Abstract: The present invention relates to a series of closed operation accupotome, including 12 types of accupotome with 33 models, each type of accupotome having an accupotome handle, an accupotome body and an accupotome head, which are connected in this order. It is characterized in that the handle, the body or the head may have various shapes depending on various diseases, and that the flat surface of the handle and the flat wedged surface of the head are in the same plane. The advantages of this invention are: entering into human body without cutting skin, to make the open surgery treatment turn into a closed surgery, and to make chemical therapy turn into physical therapy. Thus, it avoids sequelae and complications brought by the open surgery, and adverse reactions caused by the chemical medications. In addition, it improves curative effects, shortens course of diseases, simplifies therapeutic process, and saves a lot of medical expenses.