Patents Assigned to FermaLogic Inc.
  • Soybean-based fermentation media, methods of making and use
    Patent number: 8911970
    Abstract: Fermentation media containing an isoflavone-depleted soybean meal or isoflavone-depleted soybean meal product and at least one exogenous added ingredient that comprises a substrate for microbial growth are provided. Methods of making a fermentation medium comprising an isoflavone-depleted soybean meal or isoflavone-depleted soybean meal product and methods for obtaining a fermentation product are also provided. The present invention is further directed to fermentation broths obtained by the media and methods. The present invention is also directed to feed additives produced from fermentation broths obtained by the methods.
    Type: Grant
    Filed: March 19, 2013
    Date of Patent: December 16, 2014
    Assignee: Fermalogic, Inc.
    Inventor: J. Mark Weber
  • Soybean-based fermentation media, methods of making and use
    Patent number: 8426189
    Abstract: Fermentation media containing an isoflavone-depleted soybean meal or isoflavone-depleted soybean meal product and at least one exogenous added ingredient that comprises a substrate for microbial growth are provided. Methods of making a fermentation medium comprising an isoflavone-depleted soybean meal or isoflavone-depleted soybean meal product and methods for obtaining a fermentation product are also provided. The present invention is further directed to fermentation broths obtained by the media and methods. The present invention is also directed to feed additives produced from fermentation broths obtained by the methods.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: April 23, 2013
    Assignee: Fermalogic, Inc.
    Inventor: J. Mark Weber
  • Process of increasing cellular production of biologically active compounds
    Patent number: 7638306
    Abstract: A process of increasing the cellular production of biologically active compounds is provided. The process is particularly useful for increasing antibiotic production by bacterial cells. The process includes the step of inhibiting the activity of methylmalonyl-CoA mutase.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: December 29, 2009
    Assignee: Fermalogic, Inc.
    Inventors: J. Mark Weber, Andrew R. Reeves, Igor A. Brikun, William Henry Cernota
  • Process of increasing cellular production of biologically active compounds
    Publication number: 20060234958
    Abstract: A process of increasing the cellular production of biologically active compounds is provided. The process is particularly useful for increasing antibiotic production by bacterial cells. The process includes the step of inhibiting the activity of methylmalonyl-CoA mutase.
    Type: Application
    Filed: August 8, 2003
    Publication date: October 19, 2006
    Applicant: Fermalogic, Inc.
    Inventors: J. Weber, Andrew Reeves, Igor Brikun, William Cernota
  • Method for strain improvement of the erythromycin-producing bacterium
    Patent number: 6420177
    Abstract: The present invention relates to a method of improving the strain used for the production of erythromycin through the disruption of the melA gene.
    Type: Grant
    Filed: September 15, 1998
    Date of Patent: July 16, 2002
    Assignee: FermaLogic Inc.
    Inventors: J. Mark Weber, Minh B. Luu
  • Methods and compositions for enhancing erythromycin production
    Patent number: 5976836
    Abstract: The present invention provides isolated and purified polypeptides that increase antibiotic production, polynucleotides that encode those polypeptides, expression vectors containing those polynucleotides, host cells transformed with those expression vectors, a process of making the polypeptides using those polynucleotides and vectors, and processes using those polypeptides and polynucleotides.
    Type: Grant
    Filed: May 7, 1997
    Date of Patent: November 2, 1999
    Assignee: FermaLogic, Inc.
    Inventors: J. Mark Weber, Paul E. Hessler, Peter E. Larsen, Minh B. Luu
  • Process of preparing genistein
    Patent number: 5554519
    Abstract: The present invention provides a process of preparing the isoflavone genistein. Genistein is prepared by fermenting the bacteria Saccharopolyspora erythraea in the presence of a soy-based substrate. A process of recovering genistein from a bacterial fermentation medium using alkaline, organic solvent extraction is also provided.
    Type: Grant
    Filed: August 7, 1995
    Date of Patent: September 10, 1996
    Assignee: FermaLogic, Inc.
    Inventors: J. Mark Weber, Andreas Constantinou, Paul E. Hessler