Patents Assigned to Ferrokin Biosciences, Inc.
  • Polymorph forms of desazadesferrithiocin analogs
    Patent number: 9512095
    Abstract: The present invention provides a solid form and compositions thereof, which are useful as metal chelators and which exhibit desirable characteristics for the same.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: December 6, 2016
    Assignee: FERROKIN BIOSCIENCES, INC.
    Inventors: Srini Tenjarla, Paul McGee
  • POLYMORPH FORMS OF DESAZADESFERRITHIOCIN ANALOGS
    Publication number: 20150299151
    Abstract: The present invention provides a solid form and compositions thereof, which are useful as metal chelators and which exhibit desirable characteristics for the same.
    Type: Application
    Filed: December 6, 2013
    Publication date: October 22, 2015
    Applicant: FerroKin BioSciences, Inc.
    Inventors: Amy E. Tapper, Hugh Y. Rienhoff, JR., Stephan D. Parent, Patricia Andres
  • Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents
    Patent number: 9045440
    Abstract: Disclosed herein are new compounds of desazadesferrothiocin polyether (DADFT-PE) analogs, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Grant
    Filed: May 4, 2011
    Date of Patent: June 2, 2015
    Assignee: FerroKin Biosciences, Inc.
    Inventor: James Malecha
  • Oral formulations for treating metal overload
    Patent number: 8993606
    Abstract: The present invention provides, among other things, effective oral formulations based on desazadesferrithiocin polyether (DADFT-PE) analogs, salts and polymorphs thereof, as well as their application for treatment of metal overload, in particular, iron overload, and associated diseases, disorders and conditions.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: March 31, 2015
    Assignee: FerroKin Biosciences, Inc.
    Inventor: Hugh Y. Rienhoff, Jr.
  • Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
    Patent number: 8846731
    Abstract: Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogs, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Grant
    Filed: October 6, 2011
    Date of Patent: September 30, 2014
    Assignee: FerroKin Biosciences, Inc.
    Inventors: Amy E. Tapper, Hugh Y. Rienhoff, Jr., Stephan D. Parent, Patricia Andres, Jason A. Hanko, Huamin Zhang
  • Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
    Patent number: 8829197
    Abstract: Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: September 9, 2014
    Assignee: FerroKin Biosciences, Inc.
    Inventors: Amy E. Tapper, Hugh Y. Rienhoff, Jr., Stephan D. Parent, Patricia Andres, Jason A. Hanko, Huamin Zhang
  • Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
    Patent number: 8710087
    Abstract: Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: April 29, 2014
    Assignee: Ferrokin Biosciences, Inc.
    Inventors: Amy E. Tapper, Hugh Y. Rienhoff, Jr., Stephan D. Parent, Patricia Andres, Jason A. Hanko, Huamin Zhang
  • ORAL FORMULATIONS FOR TREATING METAL OVERLOAD
    Publication number: 20130225645
    Abstract: The present invention provides, among other things, effective oral formulations based on desazadesferrithiocin polyether (DADFT-PE) analogues, salts and polymorphs thereof, as well as their application for treatment of metal overload, in particular, iron overload, and associated diseases, disorders and conditions.
    Type: Application
    Filed: December 7, 2012
    Publication date: August 29, 2013
    Applicant: FerroKin BioSciences, Inc.
    Inventor: FerroKin BioSciences, Inc.
  • DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
    Publication number: 20130053387
    Abstract: Disclosed herein are new compounds of desazadesferrothiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Application
    Filed: May 4, 2011
    Publication date: February 28, 2013
    Applicant: FerroKin BioScience, Inc.
    Inventor: James W. Malecha
  • PRODRUGS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
    Publication number: 20130005781
    Abstract: Disclosed herein are new compounds of desazadesferrothiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Application
    Filed: September 5, 2012
    Publication date: January 3, 2013
    Applicant: FERROKIN BIOSCIENCES, INC.
    Inventors: John M. McCall, Hugh Y. Rienhoff, JR.
  • NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
    Publication number: 20120270911
    Abstract: Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Application
    Filed: October 6, 2011
    Publication date: October 25, 2012
    Applicant: FERROKIN BIOSCIENCES, INC.
    Inventors: Amy E. Tapper, Hugh Y. Rienhoff, Jr., Stephan D. Parent, Patricia Andres, Jason A. Hanko, Huamin Zhang
  • NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
    Publication number: 20120202857
    Abstract: Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Application
    Filed: August 4, 2011
    Publication date: August 9, 2012
    Applicant: FERROKIN BIOSCIENCES, INC.
    Inventors: Amy E. Tapper, Hugh Y. Rienhoff, JR., Stephan D. Parent, Patricia Andres, Jason A. Hanko, Huamin Zhang
  • Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
    Patent number: 8063227
    Abstract: Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: November 22, 2011
    Assignee: Ferrokin Biosciences, Inc.
    Inventors: Amy E. Tapper, Hugh Y. Rienhoff, Jr., Stephan D. Parent, Patricia Andres, Jason A. Hanko, Huamin Zhang
  • DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
    Publication number: 20110275636
    Abstract: Disclosed herein are new compounds of desazadesferrothiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Application
    Filed: May 4, 2011
    Publication date: November 10, 2011
    Applicant: FerroKin BioSciences, Inc.
    Inventor: James Malecha
  • NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
    Publication number: 20110160257
    Abstract: Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Application
    Filed: March 7, 2011
    Publication date: June 30, 2011
    Applicant: FERROKIN BIOSCIENCES, INC.
    Inventors: Amy E. Tapper, Hugh Y. Rienhoff, JR., Stephan D. Parent, Patricia Andres, Jason A. Hanko, Huamin Zhang
  • PRODRUGS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
    Publication number: 20110053993
    Abstract: Disclosed herein are new compounds of desazadesferrothiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Application
    Filed: July 26, 2010
    Publication date: March 3, 2011
    Applicant: FERROKIN BIOSCIENCES, INC.
    Inventors: John M. McCall, JR., Hugh Y. Rienhoff, JR.
  • NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
    Publication number: 20100137383
    Abstract: Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
    Type: Application
    Filed: July 14, 2009
    Publication date: June 3, 2010
    Applicant: FERROKIN BIOSCIENCES, INC.
    Inventors: Amy E. Tapper, Hugh Y. Rienhoff, JR., Stephan D. Parent, Patricia Andres, Jason A. Hanko, Huamin Zhang