Patents Assigned to FeRx Incorporated
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Patent number: 6663555Abstract: A magnet keeper-shield assembly adapted to hold and store a permanent magnet used to generate a high gradient magnetic field. Such a field may penetrate into deep targeted tumor sites in order to attract magnetically responsive micro-carriers. The magnet keeper-shield assembly includes a magnetically permeable keeper-shield with a bore dimensioned to hold the magnet. A screw driven actuator is used to push the magnet partially out of the keeper-shield. The actuator is assisted by several springs extending through the base of the keeper-shield.Type: GrantFiled: March 1, 2002Date of Patent: December 16, 2003Assignee: Ferx IncorporatedInventors: Robert Mitchiner, Thomas B. Kent, Caryn Peterson, Scott Raymond Rudge
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Publication number: 20030108614Abstract: A magnetically controllable, or guided, ferrocarbon particle composition and methods of use and production are disclosed. The composition may optionally carry biologically active substances that have been adsorbed onto the particle. The composition comprises composite, volume-compounded particles of 0.1 to 5.0 &mgr;m in size, and preferably between 0.5 and 5.0 &mgr;m, containing 1.0 to 95.0% by mass of carbon, and preferably from about 20% to about 60%. The particles may be produced by mechanical milling of a mixture of iron and carbon powders. The obtained particles are optionally placed in a solution of a biologically active substance to adsorb the substance onto the particles. The composition is generally administered in suspension.Type: ApplicationFiled: June 24, 2002Publication date: June 12, 2003Applicant: FeRx Incorporated, a Colorado corporationInventors: Viktor A. Volkonsky, Sergei D. Dvukhsherstnov, Sergei V. Chernyakov, Larry M. Allen, Thomas B. Kent
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Publication number: 20020188165Abstract: A magnet keeper-shield assembly adapted to hold and store a permanent magnet used to generate a high gradient magnetic field. Such a field may penetrate into deep targeted tumor sites in order to attract magnetically responsive micro-carriers. The magnet keeper-shield assembly includes a magnetically permeable keeper-shield with a bore dimensioned to hold the magnet. A screw driven actuator is used to push the magnet partially out of the keeper-shield. The actuator is assisted by several springs extending through the base of the keeper-shield.Type: ApplicationFiled: March 1, 2002Publication date: December 12, 2002Applicant: FeRx IncorporatedInventors: Robert K. Mitchiner, Thomas B. Kent, Caryn Peterson, Scott Raymond Rudge
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Patent number: 6488615Abstract: A magnet keeper-shield assembly adapted to hold and store a permanent magnet used to generate a high gradient magnetic field. Such a field may penetrate into deep targeted tumor sites in order to attract magnetically responsive micro-carriers. The magnet keeper-shield assembly includes a magnetically permeable keeper-shield with a bore dimensioned to hold the magnet. A screw driven actuator is used to push the magnet partially out of the keeper-shield. The actuator is assisted by several springs extending through the base of the keeper-shield.Type: GrantFiled: March 31, 2000Date of Patent: December 3, 2002Assignee: FeRx IncorporatedInventors: Robert Mitchiner, Thomas B. Kent, Caryn Peterson, Scott Raymond Rudge
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Patent number: 6482436Abstract: A magnetically controllable, or guided, ferrocarbon particle composition and methods of use and production are disclosed. The composition may optionally carry biologically active substances that have been adsorbed onto the particle. The composition comprises composite, volume-compounded particles of 0.1 to 5.0 &mgr;m in size, and preferably between 0.5 and 5.0 &mgr;m, containing 1.0 to 95.0% by mass of carbon, and preferably from about 20% to about 60%. The particles may be produced by mechanical milling of a mixture of iron and carbon powders. The obtained particles are optionally placed in a solution of a biologically active substance to adsorb the substance onto the particles. The composition is generally administered in suspension.Type: GrantFiled: January 6, 1999Date of Patent: November 19, 2002Assignee: FeRx IncorporatedInventors: Viktor A. Volkonsky, Sergei D. Dyuksherstnov, Sergi V. Chernyakov, Larry M. Allen, Thomas B. Kent
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Patent number: 6200547Abstract: A magnetically controllable, or guided, carrier composition and methods of use and production are disclosed, the composition for carrying biologically active substances to a treatment zone in a body under control of a magnetic field. The composition comprises composite, volume-compounded paclitaxel-adsorbed particles of 0.2 to 5.0 &mgr;m in size, and preferably between 0.5 and 5.0 &mgr;m, containing 1.0 to 95.0% by mass of carbon, and preferably from about 20% to about 60%. The particles are produced by mechanical milling of a mixture of iron and carbon powders. The obtained particles are placed in a solution of a biologically active substance to adsorb the substance onto the particles. The composition is generally administered in suspension. Magnetic carrier particles having therapeutic quantities of adsorbed paclitaxel, doxorubicin, Tc99, and antisense-C Myc oligonucleotide, an hematoporphyrin derivative, 6-mercaptopurine, Amphotericin B, and Camptothecin have been produced using this invention.Type: GrantFiled: January 6, 1998Date of Patent: March 13, 2001Assignee: FeRx IncorporatedInventors: Viktor A. Volkonsky, Sergei D. Dyuksherstnov, Sergi V. Chernyakov, Larry M. Allen, Thomas B. Kent