Abstract: A system and method for amplifying an information carrying signal provided on electrical supply power are provided. An input amplifier unit receives an input signal which contains an information carrying component and a supply power component. A power conversion unit is coupled to the input amplifier unit. The input amplifier unit amplifies the information carrying component of the input signal to generate an amplified signal. The power conversion unit generates at least one complementary set of offset supply levels each referenced to a non-zero offset ground level adaptively defined responsive to the electrical supply power, such that the amplified signal is referenced about the offset ground level. In certain embodiments, an output conditioning unit is employed to generate an output signal comprising an amplified version of the information carrying component of the input signal extracted from the amplified signal.