Patents Assigned to Fibrotech Therapeutics Pty Ltd
  • Fused ring analogues of anti-fibrotic agents
    Patent number: 9951087
    Abstract: The present invention relates to arylcarbonyl and heteroarylcarbonyl anthranilate compounds that may be useful as anti-fibrotic agents. The present invention also relates to methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment disorders.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: April 24, 2018
    Assignee: Fibrotech Therapeutics PTY LTD
    Inventors: Spencer John Williams, Steven Zammit, Darren James Kelly
  • Therapeutic compounds
    Patent number: 9561201
    Abstract: Substituted cinnamoyl anthranilate compounds exhibiting anti-fibrotic activity; or derivatives thereof, analogs thereof, pharmaceutically acceptable salts thereof, and metabolites thereof, with the proviso that the compound is no Tranilast.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: February 7, 2017
    Assignee: Fibrotech Therapeutics PTY LTD
    Inventors: Spencer John Williams, David Stapleton, Steven Zammit, Darren James Kelly, Richard Ernest Gilbert, Henry Krum
  • FUSED RING ANALOGUES OF ANTI-FIBROTIC AGENTS
    Publication number: 20150266893
    Abstract: The present invention relates to arylcarbonyl and heteroarylcarbonyl anthranilate compounds that may be useful as anti-fibrotic agents. The present invention also relates to methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment disorders.
    Type: Application
    Filed: June 4, 2015
    Publication date: September 24, 2015
    Applicant: Fibrotech Therapeutics PTY LTD
    Inventors: Spencer John Williams, Steven Zammit, Warren James Kelly
  • Fused ring analogues of anti-fibrotic agents
    Patent number: 9062076
    Abstract: The present invention relates to arylcarbonyl and heteroarylcarbonyl anthranilate compounds that may be useful as anti-fibrotic agents. The present invention also relates to methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment disorders.
    Type: Grant
    Filed: October 21, 2010
    Date of Patent: June 23, 2015
    Assignee: Fibrotech Therapeutics PTY LTD
    Inventors: Spencer John Williams, Steven Zammit, Darren James Kelly
  • THERAPEUTIC COMPOUNDS
    Publication number: 20140357628
    Abstract: Substituted cinnamoyl anthranilate compounds exhibiting anti-fibrotic activity; or derivatives thereof, analogues thereof, pharmaceutically acceptable salts thereof, and metabolites thereof, with the proviso that the compound is no Tranilast.
    Type: Application
    Filed: June 27, 2014
    Publication date: December 4, 2014
    Applicant: Fibrotech Therapeutics Pty Ltd
    Inventors: Spencer John Williams, David Stapleton, Steven Zammit, Darren James Kelly, Richard Ernest Gilbert, Henry Krum
  • Therapeutic compounds
    Patent number: 8765812
    Abstract: Substituted cinnamoyl anthranilate compounds exhibiting anti-fibrotic activity; or derivatives thereof, analogues thereof, pharmaceutically acceptable salts thereof, and metabolites thereof; with the proviso that the compound is not Tranilast.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: July 1, 2014
    Assignee: Fibrotech Therapeutics Pty Ltd
    Inventors: Spencer John Willams, David Stapleton, Steven Zammit, Darren James Kelly, Richard Ernest Gilbert, Henry Krum
  • FUSED RING ANALOGUES OF ANTI-FIBROTIC AGENTS
    Publication number: 20130338151
    Abstract: The present invention relates to arylcarbonyl and heteroarylcarbonyl anthranilate compounds that may be useful as anti-fibrotic agents. The present invention also relates to methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment disorders.
    Type: Application
    Filed: October 21, 2010
    Publication date: December 19, 2013
    Applicant: Fibrotech Therapeutics Pty Ltd
    Inventors: Spencer John Williams, Steven Zammit, Darren James Kelly
  • METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION
    Publication number: 20130310386
    Abstract: Methods for treating eye diseases associated with inflammation and/or vascular proliferation in subjects are disclosed. The methods include administering therapeutically effective amounts of a tranilast compound, in particular (E)-2-[[3-(3-Methoxy-4-propargyloxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or (E)-2-[[3,4-Bis(difluoromethoxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or pharmaceutically acceptable salts or solvates thereof.
    Type: Application
    Filed: November 10, 2011
    Publication date: November 21, 2013
    Applicant: Fibrotech Therapeutics Pty Ltd
    Inventors: Darren James Kelly, David Stapleton
  • FUSED RING ANALOGUES OF ANTI-FIBROTIC AGENTS
    Publication number: 20120270863
    Abstract: The present invention relates to arylcarbonyl and heteroarylcarbonyl anthranilate compounds that may be useful as anti-fibrotic agents. The present invention also relates to methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment disorders.
    Type: Application
    Filed: October 21, 2010
    Publication date: October 25, 2012
    Applicant: Fibrotech Therapeutics Pty Ltd
    Inventors: Spencer John Williams, Steven Zammit, Darren James Kelly
  • HALOGENATED ANALOGUES OF ANTI-FIBROTIC AGENTS
    Publication number: 20120059188
    Abstract: The present invention relates to halogenated compounds of formula (I) with the substituents as described within the specification. The compounds may be useful as anti-fibrotic agents. The present invention also relates to methods for their preparation.
    Type: Application
    Filed: December 19, 2008
    Publication date: March 8, 2012
    Applicants: The University of Melbourne, Fibrotech Therapeutics Pty Ltd
    Inventors: Darren James Kelly, Spencer John Williams, Steven Zammit
  • HALOGENATED ANALOGUES OF ANTI-FIBROTIC AGENTS
    Publication number: 20110021815
    Abstract: The present invention relates to halogenated compounds of formula (I) with the substituents as described within the specification. The compounds may be useful as anti-fibrotic agents. The present invention also relates to methods for their preparation.
    Type: Application
    Filed: December 19, 2008
    Publication date: January 27, 2011
    Applicants: Fibrotech Therapeutics Pty Ltd, The University of Melbourne
    Inventors: Darren James Kelly, Spencer John Williams, Steven Zammit
  • Therapeutic Compounds
    Publication number: 20100130497
    Abstract: Substituted cinnamoyl anthranilate compounds exhibiting anti-fibrotic activity; or derivatives thereof, analogues thereof, pharmaceutically acceptable salts thereof, and metabolites thereof; with the proviso that the compound is not Tranilast.
    Type: Application
    Filed: July 5, 2007
    Publication date: May 27, 2010
    Applicants: Fibrotech Therapeutics Pty Ltd, The University of Melbourne
    Inventors: Spencer John Williams, David Stapleton, Steven Zammit, Darren James, Richard Ernest, Henry Krum