Abstract: A C-axis unit for a machine tool, the C-axis unit comprising a bushing (134) adapted to be fixed to a unit support (121) of the machine tool; a head mounting platform (130) adapted to receive an operating head (40), the head mounting platform being supported by the bushing (134) and being rotatable relative to the bushing (134) around a vertical axis; a platform rotation motor (150) supported by the bushing (134) and configured to control the rotation of the head mounting platform (130); and a spindle motor (160) configured to control the rotation of a tool-carrying spindle (45) on the operating head (40) through a driving extension (163) arranged in a through-bore (133) obtained through the head mounting platform (130). The spindle motor (160) is fixed to and is rotationally integral with the head mounting platform (130).

Abstract: The pallet changing system comprises a pallet deposition and pick-up station and a pallet loading and unloading station, horizontally spaced from one another along a first horizontal direction (A-A), as well as a pallet handling unit.

Abstract: A method for checking positioning accuracy of a CNC machine with a machine tool head and a machine table using an x, y, z coordinate system, the method comprising: a) arranging a plurality of vessels on the table, the vessels in fluid connection with each other to form a system of vessels, the vessels filled with a liquid, b) mounting a distance sensor to the tool head, c) positioning the tool head to a position above the surface of the liquid in one of the vessels, d) a determining the z coordinate for which the distance sensor touches the surface of the liquid, or, for a predetermined position of the tool head in z direction above the liquid, determining the distance between the distance sensor and the liquid; steps c) and d) are repeated for each vessel to determine a z coordinate of the surface of the liquid.

Abstract: A method of determining a positioning error of a CNC machine is provided and an system thereof. A calibration element is placed within the CNC machine. A first sensor reading is taken of the calibration element. A second sensor reading is taken and the sensor is moved in a manner that the difference between the first and second sensor data decreases until the difference becomes less or equal to a pre-determined threshold value. A positioning error of the tool head is determined based on the movement of the sensor.

Abstract: A method for moving a tool of a CNC machine over a surface, wherein the CNC machine is provided with a sensor unit, comprising the steps of: (a) moving the tool over the surface in a predetermined direction and/or with a predetermined velocity and/or along a predetermined path, (b) treating the surface by the tool in accordance with a predetermined value of a treatment parameter, (c) determining, by the sensor unit, a response value indicating a response of the tool to treating the surface and/or to being pressed to the surface, and (d) determining a new direction and/or a new velocity and/or a new path and/or a new value for the treatment parameter based on the response value.

Abstract: A numerically controlled machine tool, and method for control thereof, to display virtual two-dimensional future positions to be adopted by a workpiece and by the machine tool in a pre-set predictive time window. The system and method calculate target coordinate values defining positions of the tool along axes of the machine tool on the basis of a machining program. While machining is in progress, a processor receives the calculated target coordinate values to generate and display image data on the basis of the target coordinate values and of stored mathematical models of the machine, of the workpiece, and of the tool.

Abstract: An optically-connected system is disclosed for exchanging data among industrial automation devices, that is composed of a plurality of connection modules, where each module comprises at least two pairs of optical transmitters and receivers on the main side, and one optical receiver on the opposing main side, that are opposite with respect to another pair of transmitters and receivers in a following module; and where each one of the transmitters and receivers is adapted to communicate with industrial automation devices to cooperate for exchanging data between modules, sending one interrogation signal requesting an identity of the module and the receiver is adapted to send to each corresponding response signal containing characteristics of the receiver.

Abstract: A method of determining a positioning error of a CNC machine is provided and an system thereof. A calibration element is placed within the CNC machine. A first sensor reading is taken of the calibration element. A second sensor reading is taken and the sensor is moved in a manner that the difference between the first and second sensor data decreases until the difference becomes less or equal to a pre-determined threshold value. A positioning error of the tool head is determined based on the movement of the sensor.

Abstract: An optically-connected system is disclosed for exchanging data among industrial automation devices, that is composed of a plurality of connection elements, where each element comprises at least two pairs of optical transmitters and receivers on the main side, and one optical receiver on the opposing main side, that are opposite with respect to another pair of transmitters and receivers in a following element; and where each one of the transmitters and receivers is adapted to communicate with industrial automation devices to cooperate for exchanging data between elements, sending one interrogation signal requesting an identity of the receiver and the receiver is adapted to send to each corresponding response signal containing characteristics of the receiver.

Abstract: A numerically controlled machine tool, and method for control thereof, to display virtual two-dimensional future positions to be adopted by a workpiece and by the machine tool in a pre-set predictive time window. The system and method calculate target coordinate values defining positions of the tool along axes of the machine tool on the basis of a machining program. While machining is in progress, a processor receives the calculated target coordinate values to generate and display image data on the basis of the target coordinate values and of stored mathematical models of the machine, of the workpiece, and of the tool.

Abstract: An optically-connected system is disclosed for exchanging data among industrial automation devices, that is composed of a plurality of connection modules, where each module comprises at least two pairs of optical transmitters and receivers on the main side, and one optical receiver on the opposing main side, that are opposite with respect to another pair of transmitters and receivers in a following module; and where each one of the transmitters and receivers is adapted to communicate with industrial automation devices to cooperate for exchanging data between modules, sending one interrogation signal requesting an identity of the module and the receiver is adapted to send to each corresponding response signal containing characteristics of the receiver.

Abstract: A method for moving a tool of a CNC machine over a surface, wherein the CNC machine is provided with a sensor unit, comprising the steps of: (a) moving the tool over the surface in a predetermined direction and/or with a predetermined velocity and/or along a predetermined path, (b) treating the surface by the tool in accordance with a predetermined value of a treatment parameter, (c) determining, by the sensor unit, a response value indicating a response of the tool to treating the surface and/or to being pressed to the surface, and (d) determining a new direction and/or a new velocity and/or a new path and/or a new value for the treatment parameter based on the response value.

Abstract: A system and a process are disclosed, that are automated and integrated with numerically controlled systems, for measuring, compensating and testing numerically controlled machine tool heads (1) and/or tables. The system comprises: at least one support base (11) equipped with a plurality of distance sensors (14); at least one device (16) of the gage tool type composed of an elongated cylinder (17) that is equipped at one of its ends with connection means (18) for the heads (1) and is equipped at another opposite end with a ball (20), wherein the ball (20) is placed next to the sensors (14) so that they are able, always and in any position, to measure the distance that separates them from the ball (20) and determine thereby the position in the Cartesian space.

Abstract: The present invention provides a method and system for working a workpiece with a numerically controlled machine tool having a working tool. An electronic representation of an object to be worked is read and stored. Then, the working tool is moved in real-time based on the electronic representation that is read. To move the working tool, a user provides at least one movement parameter for the working tool, where the parameter includes at least one of direction parameters, space limits, and tool movement topologies. Moreover, moving the working tool is based on the at least one parameter provided by the user, and an initial movement of the working tool occurs when the electronic representation of the object is stored and the at least one parameter for working the object is provided.

Abstract: The present invention refers to pharmaceutical compositions containing monosialoganglioside GM1 or a derivative thereof, namely, the inner ester AGF2 and the methyl ester AGF4, suitable for the treatment of Parkinson's disease. A further object of the present invention is a therapy for Parkinson's disease based on the associated administration of the aforesaid compounds and, in addition, the N-dichloroacetyl lyso GM1 (LIGA 20) with known pharmaceuticals active in the aforesaid treatment, in particular with L-dopa and/or BDNF.

Abstract: A system and a process are described for performing the Static Error Compensation on numerically controlled machine tools. The process comprises the steps of: connecting a measuring laser device (5) to a numerically controlled machine tool (1); automatically sending a point 0 of the machine (1) to the laser device (5); sending commands for taking m measure points of the machine (1) from the control (3) to the laser device (5); automatically detecting the measure points and sending consolidated data from the laser device (5) to the control (3); producing a model of static errors of the machine (1); executing the Static Error Compensation depending on said produced model.

Abstract: The invention relates to a method for amelioration of neurological outcome in humans with spinal cord damage by administration of ganglioside GM1. Another object of the present invention is to provide combination therapies for the treatment of spinal cord damage comprised of the administration of the ganglioside GM1 and other drugs which have therapeutical benefit in patients with spinal cord damage, preferably methylprednisolone.

Abstract: The present invention involves compositions for use as granular bone replacements. The compositions of the present invention are comprised of hyaluronic acid esters or salts of hyaluronic acid in association with a pharmacologically active compound wherein the molecular weight of the hyaluronic acid is below 250,000 and either artificial or natural bone granules. The present invention further involves a method of promoting the growth or repair of damaged or defective bones in either humans or animals using the compositions of hyaluronic acid derivatives and bone granules.

Abstract: Novel N-acyl-lysogangliosides obtained from gangliosides by deacyation of the ceramide group, wherein the acyl group is derived from an aliphatic acid having from 2 to 24 carbon atoms, substituted by one or more polar groups. The N-acyl-lysogangliosides of the invention exhibit an inhibiting action on protein-kinase C activation and, thus, can be utilized in therapies for various pathologies of the nervous system.

Abstract: The present invention relates to compositions containing an autocross-linked form of hyaluronic acid as a first component in a mixture with a second component noncross-linked hyaluronic acid, and possibly also in combination with another pharmacologically active substance. These compositions can be used in the treatment of arthropathies due to their unique viscoelastic properties.