Patents Assigned to Finch University of Health Sciences/The Chicago Medical School
  • Treatment of osteopetrotic diseases
    Patent number: 5641747
    Abstract: Bone resorption by osteoclast cells is promoted by activated vitamin D-binding factor, thereby providing an effective treatment for osteopetrosis. Conversely, inflammation-mediated bone loss is inhibited with antibody against the activated factor, providing a treatment for inflammation-mediated osteolytic diseases such as osteoporosis, osteoarthritis, rheumatoid arthritis and periodontal disease. The antibodies are further utilized in an antigen binding assay for diagnosing inflammation-mediated bone loss.
    Type: Grant
    Filed: July 25, 1994
    Date of Patent: June 24, 1997
    Assignees: Temple University-Of The Commonwealth System of Higher Education, Finch University of Health Sciences/The Chicago Medical School
    Inventors: Steven N. Popoff, Gary B. Schneider