Abstract: A potassium salt useful in the production of certain N-substituted alkyl or arylalkyl thionitroethenamines is produced by the reaction of the dipotassium salt of a 2-nitrodithio aliphatic acid such as 2-nitrodithio acetic acid with branched chain primary alkylamines, secondary alkylamines, arylalkylamines or heterocyclic alkylamines such as dimethylamine, pinacolylamine, benzylamine or piperonylamine, thereby converting one only of the KS-groups to an alkylamine group. The resulting monopotassium salt may be alkylated or arylalkylated to produce an N-substituted alkyl or arylalkyl thionitroethenamine. This compound may be reacted with a suitable amine to produce compounds containing the pharmaceutically active grouping --NHC(.dbd.CHNO.sub.2)NHX, wherein X represents an alkyl, arylalkyl or heterocyclic alkyl group.

Abstract: According to the invention, there is provided a process for the preparation of an aminoalkyl p-hydroxyphenyl ketone comprising reacting phenol with a nitrile, in the presence of a Lewis acid catalyst, to cause condensation thereof, the process being characterised in that the reaction is carried out in a medium comprising a nitroalkane solvent for the reactants.

Abstract: A method for the preparation of a thiazine derivative, having insecticidal properties, of the formula ##STR1## where each R is hydrogen or an appropriate aromatic or aliphatic substituent and X is hydrogen, halogen or lower alkyl, the method comprising reacting together a sulphur donor, a compound of the formula Y.sub.2 C.dbd.CXNO.sub.2 where Y is halogen (preferably chlorine) or another appropriate leaving group and a compound of the formulaH.sub.2 NCR.sub.2 CR.sub.2 CR.sub.2 OSO.sub.3 H.

Abstract: A method of preparing a thiazolidine derivative of the formula ##STR1## where R, R.sub.1, R.sub.2 R.sub.3 and R.sub.4 are each independently hydrogen or appropriate aromatic or aliphatic substituents, comprises reacting together a sulphur donor, such as sulphur or hydrogen sulphide, an aldehyde of the formula RCHO, such as benzaldehyde or formaldehyde, and an ethanolamine derivative of the formula, or including the radical, NH.sub.2 CR.sub.1 R.sub.2 CR.sub.3 R.sub.4 X, where X is a leaving group. A suitable derivative may be, for instance, aminoethylsulphate (AES). The thiazolidine derivative may be used, for example, as intermediates in the preparation of other compounds such as cysteamine.

Abstract: A method for the preparation of a thiazine derivative of the formula ##STR1## where each R is independently selected from hydrogen or a lower alkyl having 1 to 4 carbon atoms, the method comprising reacting together a sulphur donor which is selected from sulfur, ammonium or alkali metal sulfides, ammonium or alkali metal hydrosulfides, or hydrogen sulfide, 1,1-bis(methylthio)-2-nitroethene and a compound of the formulaH.sub.2 NCR.sub.2 CR.sub.2 CR.sub.2 OSO.sub.3 Hwhere each R is as defined above.A preferred method is for the preparation of tetra-2-(nitromethylene)-2H-1,3-thiazine which possesses broad spectrum insecticidal activity, and is also useful as an intermediate in the synthesis of other insecticides.