Abstract: A method and system for interoperability between mark-up language applications, executable within a browser container, includes accessing a first exchange script in the first application and a second exchange script in the second application. The method and system includes executing the applications on the processing device and executing a microservices module disposed at a desktop services layer between the first application and the browser container and between the second application and the browser container. The method and system includes communicating between the applications and the microservices module using exchange scripts, as well as determining, within the microservices module, an interaction in the first application and generating an action command for orchestrating interoperability, transferring the action command from the microservices module to the second application and performing a processing operation in the second application based on the action command.