Abstract: The present invention is directed to methods for detecting the presence of minimal or early vasculitis or other vasculopathies induced by a cox-2 inhibitor in a subject to whom a cox-2 inhibitor has been administered, selection of cox-2 inhibitory compounds, use of a cox-2 inhibitory compounds in the manufacture of anti-inflammatory medicaments, and vaccination strategies.
Type:
Grant
Filed:
November 17, 2014
Date of Patent:
August 22, 2017
Assignee:
FIRALIS SAS
Inventors:
Hueseyin Firat, Julie Boisclair, Olivier Grenet, Elias Perentes, Martin M. Schumacher