Abstract: Methods for isolating circulating small RNAs, e.g., microRNA (miRNA), from plasma samples, e.g., that comprise using an alkaline phenol:chloroform extraction, and methods of use thereof, including for the detection, prognosis, and/or monitoring of disease in a subject.
Type:
Grant
Filed:
July 29, 2015
Date of Patent:
February 20, 2018
Assignees:
University of Massachusetts, Firefly BioWorks
Inventors:
Victor Ambros, Rosalind Lee, Anthony Patrick Fusco