Abstract: 2-0- and 5-0-substituted 1.4;3.6-dianhydrohexitol mononitrates of the general formula I, ##STR1## wherein R is a halogen-substituted phenyl group, a methanesulphonyl or nicotinoyl group, as well as their physiologically acceptable acid-addition salts, insofar as R signifies the nicotinoyl group.Processes for the preparation of said compounds and pharmaceutical compositions containing said compounds.
Abstract: Aminodesoxy-1.4;3.6-dianhydrohexitol nitrates of the general formula I, ##STR1## wherein R.sup.1 and R.sup.2 possess the meanings given in claim 1, as well as their pharmacologically acceptable acid-addition salts; processes for the preparation of said compounds, and pharmaceutical compositions containing at least one of said compounds.
Type:
Grant
Filed:
July 20, 1981
Date of Patent:
December 14, 1982
Assignee:
Firma Willmar Schwabe
Inventors:
Klaus Klessing, Shyam S. Chatterjee, Bernard L. Gabard