Patents Assigned to Firmenich SA
  • Patent number: 11319272
    Abstract: The alpha alkylation of an aldehyde with a polycyclic olefin followed by a ring opening step is presented in order to provide a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof and where in R represents a hydrogen atom or C1-8 linear alkyl group; R1, R2, R3, and R4 represent, when taken separately, independently of each other, a hydrogen atom or a C1-2 linear alkyl group or a C3-4 linear or branched alkyl group; or R2 and R3, when taken together, represent a C4-10 linear, branched or cyclic alkanediyl group and n is 1 or 2 is presented.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: May 3, 2022
    Assignee: FIRMENICH SA
    Inventors: Julie Quintaine, David W. C. MacMillan
  • Publication number: 20220110351
    Abstract: The present disclosure provides compositions containing: 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxychromen-4-one (“sinensetin”); 3,5,6,7,8,3?,4?-heptamethoxyflavone (“heptamethoxyflavone” or “HMF”); 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-chromen-4-one (“nobiletin”); 5,6,7,4?-tetramethoxyflavone (“tetra-O-methylscutellarein” or “TMS”); 3,5,6,7,3?,4?-hexamethoxyflavone (“hexamethoxyquercetogetin” or “HMQ”); 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one (“tangeretin”); or any combinations thereof. The disclosure also provides uses of such compositions as mouthfeel enhancers or bitterness maskers of flavored articles, such as beverages.
    Type: Application
    Filed: October 7, 2019
    Publication date: April 14, 2022
    Applicant: Firmenich SA
    Inventors: Wen-Juan XIANG, Ronald H. SKIFF, Ke HUANG, Hui-Juan ZHANG, Long CHEN
  • Patent number: 11293040
    Abstract: Provided is a method of producing one or more sesquiterpene compounds comprising: contacting an acyclic FPP precursor with a polypeptide having terpene synthase activity, wherein the polypeptide comprises an amino acid sequence that has at least 55% sequence identity to SEQ ID NO: 1, to produce one or more terpenes selected from the group consisting of isovalencene, spirovetiva-1(10),7(11)-diene and valencene or derivatives thereof, or mixture of sesquiterpenes comprising one or more of isovalencene, spirovetiva-1(10),7(11)-diene and/or valencene; and optionally isolating the one or more terpenes or the mixture.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: April 5, 2022
    Assignee: FIRMENICH SA
    Inventors: Michel Schalk, Letizia Rocci
  • Patent number: 11291235
    Abstract: Provided herein is a method of reducing the off-taste of a food or beverage wherein the off-taste is selected from the group consisting of licorice, astringency, bitterness and sweet lingering comprising adding about 10 to about 40 ppm, phloretin to the food or beverage wherein the phloretin is provided in the substantial absence of a bitterness-masking aroma substance selected from the groups consisting of homoeriodictylol, homoeriodictyol sodium salt, homoeriodictylol potassium salt or mixtures thereof and wherein the phloretin does not significantly enhance the sweetness of the article or composition.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: April 5, 2022
    Assignee: Firmenich SA
    Inventors: Maxime Delattre, Jean-Luc Gelin, Long In Lou, Ronald H. Skiff
  • Patent number: 11293037
    Abstract: Described herein is a method of producing a drimane sesquiterpene such as albicanol, drimenol and/or derivatives thereof by contacting at least one polypeptide with farnesyl diphosphate (FPP) with a polypeptide comprising a Haloacid dehalogenase (HAD)-like hydrolase domain and having bifunctional terpene synthase activity. The method may be performed in vitro or in vivo. Also described herein are amino acid sequences of polypeptides useful in the methods and nucleic acids encoding the polypeptides described. The described method further provides host cells or organisms genetically modified to express the polypeptides and useful to produce a drimane sesquiterpene such as albicanol, drimenol and/or derivatives thereof.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: April 5, 2022
    Assignee: FIRMENICH SA
    Inventors: Michel Schalk, Pauline Anziani, Christian Goerner, Daniel Solis Escalante
  • Patent number: 11291231
    Abstract: The present invention relates to the use of a compound according to formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein n is an integer from 0 to 2; the dotted line represents a carbon-carbon single or double bond; and each of R1 to R4, when taken independently from each other, represents a hydrogen atom or represents a R5 or OR5 group, R5 representing a C1 to C5, or even a C1 to C3, alkyl group; and optionally one of the groups R1 to R4 represents —OH; and/or when R1 and R2 are taken together, and/or R3 and R4 are taken together, represent a OCH2O group, provided said groups taken together are adjacent substituents of the phenyl group; as an ingredient to confer, enhance, improve or modify the kokumi or umami taste of a flavored article.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: April 5, 2022
    Assignee: Firmenich SA
    Inventors: Eric Frerot, Kasia Aeberhardt
  • Patent number: 11291969
    Abstract: Described herein is a process for preparing microcapsules. More particularly, the process is characterized by the fact that it requires limited amounts of water for preparing microcapsules. Microcapsules obtainable by the disclosed process as well as consumer products including those microcapsules are also described.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: April 5, 2022
    Assignee: FIRMENICH SA
    Inventors: Lahoussine Ouali, Marlène Jacquemond
  • Publication number: 20220096355
    Abstract: The various aspects presented herein relate to the field of perfumery. In particular, the present disclosure provides compositions having an increased and/or improved long-lastingness and/or fragrance profile. In addition, the present disclosure provides methods of using such compositions to increase and/or improve the long-lastingness and/or fragrance profile of a fragrance composition.
    Type: Application
    Filed: May 15, 2020
    Publication date: March 31, 2022
    Applicant: Firmenich SA
    Inventors: Addi FADEL, Valery NORMAND, Artem KIRSHON, Nicholas O'LEARY, Arnaud STRUILLOU
  • Publication number: 20220079178
    Abstract: The disclosure relates generally to flavor-modified dairy compositions. In some embodiments, the flavor-modified dairy compositions comprise hydrolysis products of lactose (e.g., glucose and galactose), a flavor modifier (such as a terpene-based compound), or any combinations thereof. In some other aspects, the disclosure provides uses of a combination of lactase and a flavor modifier (such as a terpene-based compound) to modify the flavor of a dairy composition. In some related aspects, the disclosure provides methods of modifying the flavor of a dairy composition, wherein the methods include introducing a lactase and a flavor modifier (such as a terpene-based compound) to a dairy composition.
    Type: Application
    Filed: November 3, 2021
    Publication date: March 17, 2022
    Applicant: Firmenich SA
    Inventors: Mazen Moustafa, Jean-Luc Gelin, April Wong
  • Publication number: 20220079196
    Abstract: Provided herein is a method of improving the taste profile of a glucosylated terpene glycoside (GTG).
    Type: Application
    Filed: August 24, 2021
    Publication date: March 17, 2022
    Applicant: Firmenich SA
    Inventors: Wen-Juan XIANG, Dan-Ting YIN, Olivier HAEFLIGER
  • Patent number: 11267776
    Abstract: Described herein is a process including alpha alkylation of an aldehyde with a polycyclic olefin followed by a ring opening step in order to provide a compound of formula in a form of any one of its stereoisomers or a mixture thereof and where n represents 1 to 4 and R2 to R5 represent independently of each other, a hydrogen atom or a C1-6 linear alkyl group or a C3-6 branched alkyl group; and R3 and R4 or R5 or, alternatively, R2 and R3 when taken together form a saturated or unsaturated optionally substituted 5 or 6 membered carbocyclic ring.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: March 8, 2022
    Assignee: FIRMENICH SA
    Inventor: Julie Quintaine
  • Patent number: 11266172
    Abstract: The present invention relates to a new process for the preparation of powdered microcapsules encapsulating active volatile active ingredients, in particular a perfume or a flavour, said process being performed at room temperature. Powdered microcapsules obtainable by said process are also an object of the invention. Perfuming and flavouring compositions as well as consumer products comprising said capsules are also part of the invention.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: March 8, 2022
    Assignee: FIRMENICH SA
    Inventors: Pierre-Etienne Bouquerand, Amal Elabbadi, Serge Maio, Gregory Dardelle, Valery Normand
  • Patent number: 11267852
    Abstract: Provided herein is a cell line with improved odorant receptor function comprising an activated endogenous RTP1 gene, which further expresses an RTP1 protein. Further provided herein is a method for specifically activating an endogenous RTP1 gene in a eukaryotic cell using a CRISPR/Cas9 derived technique. Also provided herein is a method for identifying compounds with desired effects such as perfume or aroma modulators in said cell line.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: March 8, 2022
    Assignee: FIRMENICH SA
    Inventors: Hyo-Young Jeong, Patrick Pfister, Matthew Rogers
  • Publication number: 20220061368
    Abstract: The various aspects presented herein relate to methods and compositions for use in flavored articles containing non-animal proteins, having an improved sensory profile.
    Type: Application
    Filed: March 18, 2020
    Publication date: March 3, 2022
    Applicant: Firmenich SA
    Inventors: Jean-Luc GELIN, Patrick SALORD, Caroline ROZCZKA
  • Patent number: 11260001
    Abstract: The present disclosure relates to the field of delivery systems. More particularly, the present disclosure relates to a process for preparing a powdered composition including granules. The granules include at least one active substance present in an encapsulated form and in a non-encapsulated form. They are obtained by drying a mixture including an aqueous phase of a water-soluble polymer, a Pickering emulsion including a non-encapsulated active substance and a microcapsule slurry including an encapsulated active substance that can differ or being the same as the non-encapsulated substance. The disclosure further relates to granules obtained by the process and to products containing them.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: March 1, 2022
    Assignee: FIRMENICH SA
    Inventors: Pierre-Etienne Bouquerand, Pascal Beaussoubre, Wolfgang Fieber, François Meyer
  • Publication number: 20220015380
    Abstract: The disclosure relates generally to dairy compositions comprising lactose hydrolysis products such as preferably glucose and galactose optionally further in combination with unhydrolysed lactose, and glucosylated natural steviol glycosides. Furthermore, the disclosure relates to the used of glucosylated natural steviol glycosides to enhance the sweetness of a dairy product composition, wherein the dairy composition comprises lactose hydrolysis products. Also disclosed is a method of modifying the flavor of a dairy composition treated with lactase by introducing a glucosylated natural steviol glycoside.
    Type: Application
    Filed: December 18, 2019
    Publication date: January 20, 2022
    Applicant: Firmenich SA
    Inventors: Jean-Luc GELIN, April WONG
  • Publication number: 20220017564
    Abstract: The present disclosure generally relates to various formulations and uses of the compound Isomogroside IVE. In some aspects, the disclosure provides compositions that include Isomogroside IVE. In some embodiments, the compositions are comestible compositions, including, but not limited to, packaged food and beverage products and tabletop sweeteners. In some aspects, the disclosure provides certain compositions that include such mogroside compounds, such as compositions that include such mogroside compounds and one or more other sweeteners. In some other aspects, the disclosure provides methods of reducing the caloric content of a sweetened article, such as a sweetened food or beverage product.
    Type: Application
    Filed: April 2, 2020
    Publication date: January 20, 2022
    Applicant: Firmenich SA
    Inventors: Xian-Wen GAN, Dan-Ting YIN
  • Publication number: 20220016004
    Abstract: The present invention relates to an antiperspirant or deodorant composition comprising: an antiperspirant or deodorant active material; optionally a carrier; and a perfume composition comprising perfume raw materials; characterized in that the perfume raw materials comprises —from 0.01% to 50% by weight of a first group A of perfume raw materials having a Log P?2.5, and —from 0.01% to 50% by weight of a second group B of perfume raw materials having a Log P?4 wherein the sum of perfume raw materials of group A and perfume raw materials of group B is greater than 35% by weight based on the total weight of the perfume raw materials.
    Type: Application
    Filed: January 16, 2020
    Publication date: January 20, 2022
    Applicant: Firmenich SA
    Inventors: Mylene THERRIEN, Simon HURRY, Jane SUMMERS, Arnaud STRUILLOU
  • Publication number: 20220017563
    Abstract: The various aspects presented herein relate to processes for preparing food ingredients, flavors and sweeteners from extracts of plants that contain mogrosides such as Siraitia grosvenorii. Further provided herein are formulations and uses of compositions made from the processes.
    Type: Application
    Filed: March 24, 2020
    Publication date: January 20, 2022
    Applicant: Firmenich SA
    Inventors: Xian-Wen GAN, Dan-Ting YIN, Robert BRAUCHLI
  • Patent number: 11225629
    Abstract: Compounds of formula (I) in the form of any one of its stereoisomers or a mixture thereof are provided, wherein the dotted lines represent a carbon-carbon single bond or a carbon-carbon double bond; and one R1 group represents a hydrogen atom and the second R1 group represents a methyl group. Also provided are their uses as perfuming ingredients to impart vetiver/rooty and powdery notes; e.g. in perfuming compositions or in consumer products.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: January 18, 2022
    Assignee: FIRMENICH SA
    Inventors: Anthony Alexander Birkbeck, Pascal Millet