Abstract: The invention provides a polypeptide chain capable of forming a polyhedron by self-assembly, nanostructure polyhedra self-assembled from single polypeptide chains and a process for preparing self-assembled polyhedra from polypeptide comprising coiled-coil-forming segments in defined combination that can form dimers that form the edges of the polypeptide polyhedra within a single polypeptide chain. A defined sequence of coiled-coil-forming segments allow self-assembly into a defined polyhedral nanostructure such as a polypeptide tetrahedron.
Type:
Application
Filed:
July 29, 2012
Publication date:
October 27, 2016
Applicants:
Kemijski Institute, Fist Center Odlicnosti
Inventors:
Roman Jerala, Helena Gradisar, Sabina Bozic, Tobor Doles